Bigler E D, Kurth S M, Blatter D, Abildskov T J
Department of Psychology, Brigham Young University, Provo, Utah 84602.
Brain Res Bull. 1992 Apr;28(4):651-3. doi: 10.1016/0361-9230(92)90119-i.
Magnetic resonance (MR) scans obtained 42 days and 10 months post-injury were compared to scans obtained in similar planes three months prior to injury. In comparison to pre-injury scans, post-injury MR scan analysis demonstrated significant ventricular volume increase which is considered a measure of the degree of diffuse axonal injury. Most important, the trauma induced degenerative effects appeared to be quite complete by 42 days post-injury as there was little further degeneration that occurred between the 6 week and 10 month post-injury scans. This study demonstrates that in humans the majority of gross trauma-induced degenerative changes are complete by 6 weeks post-trauma.
将受伤后42天和10个月获得的磁共振（MR）扫描结果与受伤前三个月在相似平面获得的扫描结果进行比较。与受伤前扫描相比，受伤后MR扫描分析显示脑室容积显著增加，这被认为是弥漫性轴索损伤程度的一个指标。最重要的是，创伤诱导的退行性变化在受伤后42天似乎已经相当完整，因为在受伤后6周和10个月的扫描之间几乎没有进一步的退变发生。这项研究表明，在人类中，大多数严重创伤诱导的退行性变化在创伤后6周时已经完成。
