Troisfontaines Paul, Cornelis Guy R
Biozentrum der Universität Basel, CH-4056 Basel, Switzerland.
Physiology (Bethesda). 2005 Oct;20:326-39. doi: 10.1152/physiol.00011.2005.
The type III secretion (T3S) pathway allows bacteria to inject effector proteins into the cytosol of target animal or plant cells. T3S systems evolved into seven families that were distributed among Gram-negative bacteria by horizontal gene transfer. There are probably a few hundred effectors interfering with control and signaling in eukaryotic cells and offering a wealth of new tools to cell biologists.
III型分泌（T3S）途径使细菌能够将效应蛋白注入靶动物或植物细胞的细胞质中。T3S系统进化为七个家族，通过水平基因转移分布在革兰氏阴性菌中。可能有数百种效应蛋白干扰真核细胞中的调控和信号传导，为细胞生物学家提供了大量新工具。
