Onishi Joji, Suzuki Yusuke, Yoshiko Kenichi, Hibino Shin, Iguchi Akihisa
Department of Geriatrics, Nagoya University Graduate School of Medicine, Nagoya, Aichi, 466-8550, Japan.
Cogn Behav Neurol. 2005 Sep;18(3):179-84. doi: 10.1097/01.wnn.0000178227.54315.38.
To assess the utility of quantitative electroencephalographic analysis as an indicator of cognitive impairment, we examined the correlation between Mini-Mental State Examination (MMSE) scores and quantitative electroencephalographic (QEEG) power values in elderly patients and constructed a regression model to predict MMSE scores.
Because of the growing number of elderly individuals with cognitive deficits, there is an increasing need for simple and objective methods with which to evaluate cognitive function. Although QEEG is reportedly a useful method for this purpose, few researchers have constructed a QEEG-based model for predicting the degree of cognitive impairment in clinical settings.
We evaluated brain function using QEEG in 44 elderly patients with memory complaints and compared the results with their MMSE scores.
In the correlation analysis, no significant correlation was found between MMSE scores and QEEG power values. However, a regression model created using relative QEEG and gender for predicting MMSE scores had an adjusted R2 of 0.471.
This finding suggests that QEEG analysis may be a useful indicator of cognitive decline in patients with memory complaints.
为评估定量脑电图分析作为认知障碍指标的效用，我们研究了老年患者简易精神状态检查表（MMSE）得分与定量脑电图（QEEG）功率值之间的相关性，并构建了一个回归模型来预测MMSE得分。
由于认知功能缺损的老年人数量不断增加，对用于评估认知功能的简单且客观的方法的需求日益增长。尽管据报道定量脑电图是用于此目的的一种有用方法，但很少有研究人员构建基于定量脑电图的模型来预测临床环境中的认知障碍程度。
我们对44名有记忆问题主诉的老年患者使用定量脑电图评估脑功能，并将结果与其MMSE得分进行比较。
在相关性分析中，未发现MMSE得分与QEEG功率值之间存在显著相关性。然而，使用相对QEEG和性别创建的用于预测MMSE得分的回归模型的调整后R²为0.471。
这一发现表明，定量脑电图分析可能是有记忆问题主诉患者认知衰退的一个有用指标。
Zotero 插件