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现代多探测器CT扫描仪中加权CT剂量指数的测定。

Determination of the weighted CT dose index in modern multi-detector CT scanners.

作者信息

Perisinakis K, Damilakis J, Tzedakis A, Papadakis A, Theocharopoulos N, Gourtsoyiannis N

机构信息

Department of Medical Physics, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece.

出版信息

Phys Med Biol. 2007 Nov 7;52(21):6485-95. doi: 10.1088/0031-9155/52/21/010. Epub 2007 Oct 16.

Abstract

The aim of the present study was to (a) evaluate the underestimation in the value of the free-in-air (CTDI(air)) and the weighted CT dose index (CTDI(w)) determined with the standard 100 mm pencil chamber, i.e. the CTDI(100) concept, for the whole range of nominal radiation beam collimations selectable in a modern multi-slice CT scanner, (b) estimate the optimum length of the pencil-chamber and phantoms for accurate CTDI(w) measurements and (c) provide CTDI(w) values normalized to free-in-air CTDI for different tube-voltage, nominal radiation beam collimations and beam filtration values. The underestimation in the determination of CTDI(air) and CTDI(w) using the CTDI(100) concept was determined from measurements obtained with standard polymethyl-methacrylate (PMMA) phantoms and arrays of thermoluminescence dosimeters. The Monte Carlo N-Particle transport code was used to simulate standard CTDI measurements on a 16-slice CT scanner. The optimum pencil-chamber length for accurate determination of CTDI(w) was estimated as the minimum chamber length for which a further increase in length does not alter the value of the CTDI. CTDI(w)/CTDI(air) ratios were determined using Monte Carlo simulation and the optimum detector length for all selectable tube-voltage values and for three different values of beam filtration. To verify the Monte Carlo results, measured values of CTDI(w)/CTDI(air) ratios using the standard 100 mm pencil ionization chamber were compared with corresponding values calculated with Monte Carlo experiments. The underestimation in the determination of CTDI(air) using the 100 mm pencil chamber was less than 1% for all beam collimations. The underestimation in CTDI(w) was 15% and 27% for head and body phantoms, respectively. The optimum detector length for accurate CTDI(w) measurements was found to be 50 cm for the beam collimations commonly employed in modern multi-detector (MD) CT scanners. The ratio of CTDI(w)/CTDI(air) determined using the optimum detector length was found to be independent of beam collimation. Percentage differences between measured and calculated corresponding CTDI(w)/CTDI(air) ratios were always less than 8% for head and less than 5% for body PMMA phantoms. In conclusion, the CTDI(air) of MDCT scanners may be measured accurately with a 100 mm pencil chamber. However, the CTDI(100) concept was found to be inadequate for accurate CTDI(w) determination for the wide beam collimations commonly used in MDCT scanners. Accurate CTDI(w) determination presupposes the use of a pencil chamber and PMMA phantoms at least 50 cm long.

摘要

本研究的目的是

(a) 评估在现代多层CT扫描仪中可选择的整个标称辐射束准直范围内,使用标准100毫米笔形电离室(即CTDI(100)概念)确定的空气比释动能(CTDI(air))和加权CT剂量指数(CTDI(w))值的低估情况;(b) 估计用于准确测量CTDI(w)的笔形电离室和体模的最佳长度;(c) 提供针对不同管电压、标称辐射束准直和束流过滤值,归一化为空气比释动能CTDI的CTDI(w)值。使用CTDI(100)概念测定CTDI(air)和CTDI(w)时的低估情况,是根据用标准聚甲基丙烯酸甲酯(PMMA)体模和热释光剂量计阵列获得的测量结果确定的。蒙特卡罗N粒子输运代码用于在16层CT扫描仪上模拟标准CTDI测量。准确测定CTDI(w)的最佳笔形电离室长度估计为长度进一步增加不会改变CTDI值的最小室长。使用蒙特卡罗模拟确定CTDI(w)/CTDI(air)比值,并确定所有可选择管电压值和三种不同束流过滤值的最佳探测器长度。为验证蒙特卡罗结果,将使用标准100毫米笔形电离室测量的CTDI(w)/CTDI(air)比值的测量值与蒙特卡罗实验计算的相应值进行比较。对于所有束准直,使用100毫米笔形电离室测定CTDI(air)时的低估小于1%。头部和体部体模CTDI(w)的低估分别为15%和27%。发现对于现代多探测器(MD)CT扫描仪中常用的束准直,准确测量CTDI(w)的最佳探测器长度为50厘米。发现使用最佳探测器长度确定的CTDI(w)/CTDI(air)比值与束准直无关。对于头部PMMA体模,测量和计算的相应CTDI(w)/CTDI(air)比值之间的百分比差异始终小于8%,对于体部PMMA体模则小于5%。总之,MDCT扫描仪的CTDI(air)可用100毫米笔形电离室准确测量。然而,发现CTDI(100)概念不足以准确测定MDCT扫描仪中常用的宽束准直的CTDI(w)。准确测定CTDI(w)需要使用笔形电离室和至少50厘米长的PMMA体模。

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