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[广西64例中国HIV/AIDS患者口腔病损调查]

[Investigation on oral lesions in 64 Chinese HIV/AIDS patients in Guangxi province].

作者信息

Tao Ren-Chuan, Deng Hua-Jie, Ya Zu-Ke, Guo Su-Zhen, Liang Shu-Xiong, Liu Wei

机构信息

Dept. of Oral Medicine, Affiliated Stomatology Hospital of Guangxi Medical University, Nanning 530021, China.

出版信息

Hua Xi Kou Qiang Yi Xue Za Zhi. 2005 Aug;23(4):338-40.

Abstract

OBJECTIVE

To investigate the prevalence, age and gender distribution and clinical features of HIV/AIDS oral lesions in patients in Guangxi province, and to provide the epidemiological information for prevention and treatment of these diseases in the certain population.

METHODS

A total of 64 HIV/AIDS patients were included in this study. All patients HIV serum-status was confirmed in Guangxi Center of Disease Control (GXCDC). Oral examination was carried out by standardized specialists. HIV/AIDS orofacial lesions were recorded and diagnosed using the EC Clearing House Criteria on Oral Problems related to HIV Infection (1992).

RESULTS

Among the total of 64 HIV/AIDS patients included in this study, there were 53 males and 11 females, with mean age of 36.1 years. Candidiasis was the most common lesion with the pseudomembranous type predominating. High prevalences of xerostomia, 11 oral ulceration and 7 HIV related periodontitis were noted. 6 Herpetic stomatitis and 3 herpes zoster, 2 oral hairy leukoplakia and 1 Kaposi's sarcoma and 1 lymphadentitis also were found.

CONCLUSION

This study shows a high prevalence of candidiasis, salivary gland disease. Maybe oral ulceration prevalence is not increased, but lesion severity is increased with more severe heperiform or major RAU. It suggested that HIV/AIDS usually shows oral lesion and partly can appear in early phase.

摘要

目的

调查广西地区艾滋病病毒/艾滋病(HIV/AIDS)患者口腔病损的患病率、年龄及性别分布和临床特征,为该特定人群这些疾病的防治提供流行病学资料。

方法

本研究共纳入64例HIV/AIDS患者。所有患者的HIV血清学状态均在广西壮族自治区疾病预防控制中心(GXCDC)得到确认。由标准化的专科医生进行口腔检查。使用欧洲共同体口腔问题信息中心关于HIV感染相关口腔问题的标准(1992年)记录并诊断HIV/AIDS患者的口腔颌面部病损。

结果

本研究纳入的64例HIV/AIDS患者中,男性53例,女性11例,平均年龄36.1岁。念珠菌病是最常见的病损,以假膜型为主。口干症、11例口腔溃疡和7例HIV相关性牙周炎的患病率较高。还发现6例疱疹性口炎和3例带状疱疹、2例口腔毛状白斑、1例卡波西肉瘤和1例淋巴结炎。

结论

本研究显示念珠菌病、唾液腺疾病的患病率较高。口腔溃疡患病率可能未增加,但随着疱疹样或重型复发性阿弗他溃疡(RAU)病情加重,病损严重程度增加。提示HIV/AIDS患者常出现口腔病损,部分可在早期出现。

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