Small molecule macroarray construction via Ugi four-component reactions.
作者信息
Lin Qi, O'Neill Jennifer C, Blackwell Helen E
机构信息
Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin 53706-1322, USA.
出版信息
Org Lett. 2005 Sep 29;7(20):4455-8. doi: 10.1021/ol051684o.
PMID:16178557
Abstract
[reaction: see text] We report the construction of small molecule macroarrays via Ugi four-component reactions on planar cellulose supports. Array synthesis was enabled by the development of a high efficiency photocleavable linker system and the strategic use of both water- and microwave-assisted organic reactions.
摘要
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