趋化因子信号传导确定了治疗干预的新靶点。
Chemokine signaling defines novel targets for therapeutic intervention.
作者信息
Rodríguez-Frade José Miguel, Martínez-A Carlos, Mellado Mario
机构信息
Department of Immunology and Oncology, National Center of Biotechnology, CSIC, Campus Universitario de Cantoblanco, E-28049 Madrid, Spain.
出版信息
Mini Rev Med Chem. 2005 Sep;5(9):781-9. doi: 10.2174/1389557054867084.
PMID:16178721
Abstract
Members of the human chemokine family are considered a suitable target for therapeutic intervention, as they have a fundamental role in several important human diseases. Here we outline potential new areas of intervention based on recent findings on chemokine receptor function.
摘要
人类趋化因子家族的成员被认为是治疗干预的合适靶点，因为它们在几种重要的人类疾病中起着重要作用。在此，我们根据趋化因子受体功能的最新研究结果概述潜在的新干预领域。
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