Omoti C E, Halim N K D
Department of Haematology, University of Benin Teaching Hospital, Benin City, Nigeria.
Clin Lab Haematol. 2005 Oct;27(5):302-6. doi: 10.1111/j.1365-2257.2005.00711.x.
The clinicopathologic features of malignant lymphomas had not been documented in the Niger Delta region of Nigeria, which is known for its petrochemical industries and gas flare sites. Cases of lymphomas that presented to the University of Benin Teaching Hospital (UBTH), a major referral centre in the region, from January 1990 to December 2003 were reviewed. Demographic and clinical information were obtained from the case files. Diagnosis was established based on the histological examination of an accessible biopsy lymph node and classified according to the Working Formulation (WF). Haematological parameters were done using an automated Coulter counter. Non-Hodgkin's lymphoma (NHL) occurred predominantly in young adults (20-39 years). A majority of the patients presented in the advanced stage of the disease (Stages III-IV) according to the Ann Arbor system and a performance status (PS) scale of 2-4. The intermediate grade NHL (41.2%) formed the largest group of which diffuse large cell lymphoma (DLCL) was the most commonly observed histopathologic type followed by the large cell immunoblastic type.
恶性淋巴瘤的临床病理特征在尼日利亚的尼日尔三角洲地区尚未有记录，该地区以其石化工业和天然气燃烧点而闻名。对1990年1月至2003年12月期间在该地区主要转诊中心贝宁大学教学医院（UBTH）就诊的淋巴瘤病例进行了回顾。从病例档案中获取人口统计学和临床信息。根据可获取的活检淋巴结的组织学检查进行诊断，并按照工作分类法（WF）进行分类。血液学参数使用自动库尔特计数器进行检测。非霍奇金淋巴瘤（NHL）主要发生在年轻人（20 - 39岁）中。根据安阿伯系统，大多数患者在疾病晚期（III - IV期）就诊，且体能状态（PS）评分为2 - 4。中级NHL（41.2%）构成最大的组，其中弥漫性大细胞淋巴瘤（DLCL）是最常观察到的组织病理学类型，其次是大细胞免疫母细胞型。
