由于血红蛋白OSU - 克里斯蒂安斯堡导致糖化血红蛋白[HbA1C]假性升高。

Falsely high glycated haemoglobin [HbA1C] because of haemoglobin OSU-Christiansborg.

作者信息

Kapoor D, Ng J P, Jones T H

机构信息

Centre for Diabetes and Endocrinology, Department of Haematology, Barnsley District General Hospital, Barnsley, UK.

出版信息

Clin Lab Haematol. 2005 Oct;27(5):334-5. doi: 10.1111/j.1365-2257.2005.00718.x.

DOI:10.1111/j.1365-2257.2005.00718.x

PMID:16178917

Abstract

Glycated haemoglobin (HbA1c) is routinely used to assess the degree of glycaemic control in diabetic patients. We report a case of a 73 year old diabetic woman who had an elevated HbA1c of 13.4%. She was on maximum oral hypoglycaemic agents and was commenced on insulin. However, her HbA1c continued to remain high at 20.4%. Subsequent tests revealed that she had a haemoglobin variant, Haemoglobin Osu-Christiansborg, causing the falsely high glycated haemoglobin.

摘要

糖化血红蛋白（HbA1c）通常用于评估糖尿病患者的血糖控制程度。我们报告一例73岁的糖尿病女性病例，其糖化血红蛋白水平升高至13.4%。她正在服用最大剂量的口服降糖药，并开始使用胰岛素治疗。然而，她的糖化血红蛋白仍持续居高不下，达到20.4%。后续检查发现她存在一种血红蛋白变异体——奥斯-克里斯蒂安斯堡血红蛋白，导致糖化血红蛋白假性升高。