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[转移性肾癌的非典型部位。文献综述]

[Atypical sites of metastatic renal carcinoma. Literature review].

作者信息

Pérez Fentes D A, Blanco Parra M, Toucedo Caamaño V, Lema Grille J, Cimadevila García A, Villar Núñez M

机构信息

Servicio de Urología, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela.

出版信息

Actas Urol Esp. 2005 Jul-Aug;29(7):621-30. doi: 10.1016/s0210-4806(05)73312-x.

Abstract

OBJECTIVE

To review in the literature atypical sites of metastatic renal cell carcinoma, its onset, clinical features, diagnosis, treatment and prognosis.

METHODS

To review, using Medline database, atypical sites of metastatic renal cell carcinoma in the last five years Spanish literature.

RESULTS

There have been published 15 spanish articles about atypical metastatic renal cell carcinoma in the last five years. Most patients were male with a mean age of 62,3 years and methacronous metastases. Imaging and pathological diagnosis. Main sites: ocular, renal graft, larynx, suprarenal, brain, penis, gastric and pancreatic. Surgical treatment if the surgeon is able to remove the lesion. Inmunotherapy and radiotherapy in the rest of cases.

CONCLUSIONS

Renal cell carcinoma represents about 3% of all adult malignancy neoplasms. Its metastatic sites, in order of frequency, are lung, bone and liver, whether synchronic or methacronic. Its location, clinical features, onset, evolution and prognosis is very variable. Individualized diagnostic and therapeutic approach, according to prognostic factors. The knowledge of this atypical sites in patients with renal cell carcinoma in the past can lead us to an earlier diagnosis and treatment which could change the evolution of the illness.

摘要

目的

回顾文献中转移性肾细胞癌的非典型转移部位、发病情况、临床特征、诊断、治疗及预后。

方法

利用Medline数据库回顾过去五年西班牙文献中转移性肾细胞癌的非典型转移部位。

结果

过去五年发表了15篇关于非典型转移性肾细胞癌的西班牙文文章。大多数患者为男性,平均年龄62.3岁,有异时性转移。通过影像学和病理诊断。主要转移部位:眼部、肾移植部位、喉部、肾上腺、脑、阴茎、胃和胰腺。若外科医生能够切除病灶,则进行手术治疗。其余病例采用免疫治疗和放疗。

结论

肾细胞癌约占所有成人恶性肿瘤的3%。其转移部位,按频率依次为肺、骨和肝,无论是同时性还是异时性转移。其位置、临床特征、发病情况、病情发展及预后差异很大。根据预后因素采取个体化的诊断和治疗方法。了解肾细胞癌患者过去的这些非典型转移部位可使我们更早地进行诊断和治疗,从而改变疾病的发展进程。

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