Stanton Susan G, Ryerson Elizabeth, Moore Shana L, Sullivan-Mahoney Maureen, Couch Sarah C
Communication Sciences and Disorders, University of Cincinnati, Cincinnati, OH 45267-0379, USA.
Am J Audiol. 2005 Jun;14(1):86-93. doi: 10.1044/1059-0889(2005/008).
Hearing screening results for newborns of diabetic mothers were compared with those of nondiabetic controls.
This study was a retrospective chart review of mothers with pregestational diabetes mellitus and their neonates (n=73) who received newborn hearing screening between January 1, 2000, and May 1, 2002. A group of nondiabetic mothers and their infants (n=73), with birth dates that matched the diabetic group, served as controls. A 2-tiered hearing screening protocol, employing distortion product otoacoustic emission (DPOAE) and automated auditory brainstem response (A-ABR) screening techniques, was used.
The DPOAE screening failure rate was 5.5% (4/73) for babies in the nondiabetic control group and 11.0% (8/73) for infants of diabetic mothers; this difference was not statistically significant. The A-ABR failure rate was 9.1% (1/11) for the diabetic group compared with 0% (0/4) for the controls, but the A-ABR was measured for only a small number of participants in each group. The frequency of premature birth and abnormal birth weight was significantly greater for the infants of diabetic mothers compared with controls.
Given the greater frequency of prematurity and abnormal birth weight in the population of neonates born to diabetics, additional research using A-ABR is recommended.
比较糖尿病母亲新生儿与非糖尿病对照新生儿的听力筛查结果。
本研究是一项对2000年1月1日至2002年5月1日期间接受新生儿听力筛查的孕前糖尿病母亲及其新生儿（n = 73）的回顾性病历审查。一组出生日期与糖尿病组匹配的非糖尿病母亲及其婴儿（n = 73）作为对照。采用了一种两级听力筛查方案，使用畸变产物耳声发射（DPOAE）和自动听性脑干反应（A - ABR）筛查技术。
非糖尿病对照组婴儿的DPOAE筛查失败率为5.5%（4/73），糖尿病母亲的婴儿为11.0%（8/73）；这种差异无统计学意义。糖尿病组的A - ABR失败率为9.1%（1/11），而对照组为0%（0/4），但每组中仅对少数参与者进行了A - ABR测量。与对照组相比，糖尿病母亲的婴儿早产和出生体重异常的频率明显更高。
鉴于糖尿病母亲所生新生儿群体中早产和出生体重异常的频率更高，建议使用A - ABR进行更多研究。
