Abid Abdul Rehman, Mallick Nadeem Hayat, Shahbaz Ahmad, Tarin Siraj Ahmed Munir
Department of Cardiology, Punjab Institute of Cardiology, Lahore, Pakistan.
J Coll Physicians Surg Pak. 2005 Sep;15(9):524-7.
To evaluate the in-hospital mortality and complications of acute myocardial infarction in diabetic and non-diabetic patients.
Descriptive study.
Coronary Care Unit and Cardiology Ward of Nishtar Hospital, Multan from 1st October 2002 till 15th May 2003.
Four hundred and forty-eight (448) consecutive patients who fulfilled the inclusion criteria were studied while they were admitted to the hospital. Patients were divided into two groups of diabetics and non-diabetics depending on the presence of diabetes mellitus. In-hospital mortality and complications were compared between the two groups by Chi-square method.
Diabetic patients presented in more advanced Killip class as 32(26.7%) patients presented in Killip class II, 13(10.8%) patients presented in Killip class III and 6(5%) patients presented in Killip class IV. In the non-diabetic group, 68(20.7%), 24(7.3%) and 11(3.4%) patients presented in these Killip classes respectively (p<0.042). The total in-hospital mortality was 17%. Mortality was 28(23.3%) in diabetics and 48(14.6%) in non-diabetics (p<0.03). In-hospital mortality was almost double in diabetics as compared to non-diabetics. Mechanical complications were observed in 42(35%) patients in diabetic group and 80(24.4%) patients in non-diabetic group. Left ventricular failure was the most commonly observed mechanical complication. Electrical complications were observed in 84(70%) diabetic and 162(49.4%) non-diabetic patients (p<0.205).
In patients with acute myocardial infarction, presence of diabetes mellitus was associated with worse in-hospital outcome leading to increased mortality and complications as compared to non-diabetic patients.
评估糖尿病患者和非糖尿病患者急性心肌梗死的院内死亡率及并发症情况。
描述性研究。
2002年10月1日至2003年5月15日期间，木尔坦尼什塔尔医院冠心病监护病房及心脏病科病房。
对448例符合纳入标准的连续入院患者进行研究。根据是否患有糖尿病将患者分为糖尿病组和非糖尿病组。采用卡方检验比较两组的院内死亡率及并发症情况。
糖尿病患者中，32例（26.7%）处于Killip分级II级，13例（10.8%）处于Killip分级III级，6例（5%）处于Killip分级IV级，提示病情更严重。在非糖尿病组中，分别有68例（20.7%）、24例（7.3%）和11例（3.4%）患者处于这些Killip分级（p<0.042）。院内总死亡率为17%。糖尿病患者死亡率为28例（23.3%），非糖尿病患者死亡率为48例（14.6%）（p<0.03）。糖尿病患者的院内死亡率几乎是非糖尿病患者的两倍。糖尿病组42例（35%）患者出现机械性并发症，非糖尿病组80例（24.4%）患者出现机械性并发症。左心室衰竭是最常见的机械性并发症。糖尿病患者中有84例（70%）出现电并发症，非糖尿病患者中有162例（49.4%）出现电并发症（p<0.205）。
急性心肌梗死患者中，与非糖尿病患者相比，糖尿病的存在与更差的院内结局相关，导致死亡率和并发症增加。
