Sarwar Shahid, Khan Anwaar A, Alam Altaf, Butt Arshad Kamal, Shafqat Farzana, Malik Kashif, Ahmad Irfan, Niazi Aamir Khan
Department of Gastroenterology and Hepatology, Shaikh Zayed Postgraduate Medical Institute, Lahore, Pakistan.
J Coll Physicians Surg Pak. 2005 Sep;15(9):528-31.
To identify hematological, biochemical and ultrasonographic predictors of esophageal varices in patients of cirrhosis.
Cross-sectional, analytical study.
Department of Gastroenterology, Shaikh Zayed Postgraduate Medical Institute, Lahore, from September 2003 to March 2004.
One hundred and one patients with established cirrhosis and no history of variceal bleed underwent physical examination, hematological, biochemical tests and abdominal ultrasound examination. Esophagogastroduodenoscopy (EGD) was carried out in all patients. Presence of varices on EGD was correlated with hematological, biochemical and ultrasonographic variables by regression analysis.
Esophageal varices were seen in 65 patients while 36 patients had no varices. High grade varices were seen in 15 patients and 50 patients had low grade varices. Serum albumin less than 2.95 g/dl, platelet count less than 88 x 103/muL and portal vein diameter more than 11 mm were associated with presence of varices. High grade varices were predicted by serum albumin < 2.95 g/dl and portal vein diameter more than 11 mm.
Patients with serum albumin < 2.95 g/dl, platelet count < 88 x 103/muL and portal vein diameter > 11 mm are more likely to have high grade varices. These patients are candidates for surveillance endoscopy.
确定肝硬化患者食管静脉曲张的血液学、生化及超声预测指标。
横断面分析研究。
2003年9月至2004年3月，拉合尔谢赫·扎耶德研究生医学研究所胃肠病科。
101例确诊肝硬化且无静脉曲张出血史的患者接受了体格检查、血液学、生化检查及腹部超声检查。所有患者均进行了食管胃十二指肠镜检查（EGD）。通过回归分析将EGD检查中静脉曲张的存在情况与血液学、生化及超声变量进行关联。
65例患者可见食管静脉曲张，36例患者无静脉曲张。15例患者有高度静脉曲张，50例患者有低度静脉曲张。血清白蛋白低于2.95 g/dl、血小板计数低于88×10³/μL及门静脉直径超过11 mm与静脉曲张的存在相关。血清白蛋白<2.95 g/dl及门静脉直径超过11 mm可预测高度静脉曲张。
血清白蛋白<2.95 g/dl、血小板计数<88×10³/μL及门静脉直径>11 mm的患者更易发生高度静脉曲张。这些患者是监测性内镜检查的对象。
