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异位妊娠:临床表现与危险因素

Ectopic pregnancy: presentation and risk factors.

作者信息

Shah Nusrat, Khan Nusrat H

机构信息

Department of Obstetrics and Gynaecology, Unit III, Civil Hospital, Karachi, Pakistan.

出版信息

J Coll Physicians Surg Pak. 2005 Sep;15(9):535-8.

Abstract

OBJECTIVE

To describe the clinical features and risk factors in ectopic pregnancy.

DESIGN

A descriptive study.

PLACE AND DURATION OF STUDY

The study was conducted in Unit III of the Department of Obstetrics and Gynaecology, Civil Hospital, Karachi from January 2002 to December 2003.

PATIENTS AND METHODS

A total of 38 women diagnosed with ectopic pregnancy were included in the study. Data was retrieved from the charts of all the patients diagnosed with ectopic pregnancy through a structured proforma. The variables studied included age, parity, symptoms and signs, risk factors, treatment and associated maternal morbidity.

RESULTS

Among the clinical features, the most common presenting symptom was abdominal pain in 37 (97.3%) patients whereas history of amenorrhea and vaginal bleeding were found in 28 (73.6%) and 22 (57.8%) patients respectively. The most common physical sign was tenderness: abdominal tenderness in 28 (73.6%) and pelvic tenderness in 23 (60.5%) patients. Cervical excitation was only present in 19 (50%) patients. Risk factors were present in 23 patients (60.5%), the most frequent being infertility in 9 patients (23.6%). Other risk factors were tuberculosis in 6 patients (15.7%), previous ectopic pregnancy in 3 (7.8%) and previous tubal surgery in 1 (2.6%) patient. History of IUCD was present in 1 (2.6%), injection Depo-provera in 4 (10.5%) and OCP in 3 (7.8%) patients. History of D & C and C-section were present in 7 (18.4%) and 4 (10.5%) patients respectively.

CONCLUSION

Abdominal pain was the single most consistent feature of ectopic pregnancy. Risk factors may not always be present. Therefore, ectopic pregnancy should be suspected in every woman of reproductive age who presents with unexplained abdominal pain, irrespective of amenorrhea and vaginal bleeding and whether risk factors were present in the past history or not.

摘要

目的

描述异位妊娠的临床特征及危险因素。

设计

描述性研究。

研究地点及时间

本研究于2002年1月至2003年12月在卡拉奇市民医院妇产科第三单元开展。

患者及方法

本研究共纳入38例诊断为异位妊娠的女性。通过结构化表格从所有诊断为异位妊娠患者的病历中检索数据。研究的变量包括年龄、产次、症状和体征、危险因素、治疗及相关孕产妇发病率。

结果

在临床特征中,最常见的症状是腹痛,37例(97.3%)患者出现腹痛,而分别有28例(73.6%)和22例(57.8%)患者有闭经和阴道流血史。最常见的体征是压痛:28例(73.6%)患者有腹部压痛,23例(60.5%)患者有盆腔压痛。仅19例(50%)患者有宫颈举痛。23例(60.5%)患者存在危险因素,最常见的是9例(23.6%)患者不孕。其他危险因素包括6例(15.7%)患者有结核病,3例(7.8%)患者有既往异位妊娠史,1例(2.6%)患者有既往输卵管手术史。1例(2.6%)患者有宫内节育器使用史,4例(10.5%)患者有注射醋酸甲羟孕酮史,3例(7.8%)患者有口服避孕药史。分别有7例(18.4%)和4例(10.5%)患者有刮宫和剖宫产史。

结论

腹痛是异位妊娠最一致的单一特征。危险因素不一定总是存在。因此,对于每一位出现不明原因腹痛的育龄女性,无论有无闭经和阴道流血,也无论既往史中是否存在危险因素,均应怀疑异位妊娠。

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