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在迪拜一家三级医院评估异位妊娠的药物和手术治疗方法。

Evaluating Medical and Surgical Treatments for Ectopic Pregnancy at a Tertiary Hospital in Dubai.

作者信息

Akbari Elham A

机构信息

Obstetrics and Gynecology, Latifa Hospital, Dubai, ARE.

出版信息

Cureus. 2024 Sep 11;16(9):e69216. doi: 10.7759/cureus.69216. eCollection 2024 Sep.

Abstract

INTRODUCTION

The current data about ectopic pregnancy in the UAE is limited, including the incidence, method of management, and its effectiveness. This study aimed to determine the frequency of medical and surgical management in the treatment of ectopic pregnancy and the efficacy of each modality used.

METHOD

Two hundred and nine patients were diagnosed with ectopic pregnancies in the years 2018 and 2019 in Latifa Hospital and were included in this study. The patients were treated with either intramuscular injection of methotrexate (single or two doses) or surgical management.

RESULTS

Methotrexate was administered to 101 patients (48%). In 77 patients (76%), a single dose of methotrexate was administered, and in 24 patients (24%), two doses of methotrexate were administered. In the single-dose group, 75.3% (58 out of 77 patients) were successfully treated and completely recovered. While in the two-dose group, the success rate was 58.3% (14 out of 24 patients). On the other hand, among patients who underwent surgical management, the success rate was 97.2% (105 out of 108 patients). The difference in the success rates was statistically significant.

CONCLUSION

The results of the study showed that medical and surgical management were used almost equally in managing patients with ectopic pregnancy (48% vs. 52%, respectively). Furthermore, it was shown that single-dose methotrexate treatment was more successful than two doses. However, surgical management had the highest success rate among the three modalities.

摘要

引言

阿联酋目前关于异位妊娠的数据有限,包括发病率、治疗方法及其有效性。本研究旨在确定异位妊娠治疗中药物治疗和手术治疗的频率以及每种治疗方式的疗效。

方法

2018年和2019年在拉蒂法医院诊断出209例异位妊娠患者并纳入本研究。这些患者接受了肌肉注射甲氨蝶呤(单剂量或两剂量)或手术治疗。

结果

101例患者(48%)接受了甲氨蝶呤治疗。77例患者(76%)接受了单剂量甲氨蝶呤治疗,24例患者(24%)接受了两剂量甲氨蝶呤治疗。在单剂量组中,75.3%(77例患者中的58例)成功治疗并完全康复。而在两剂量组中,成功率为58.3%(24例患者中的14例)。另一方面,在接受手术治疗的患者中,成功率为97.2%(108例患者中的105例)。成功率的差异具有统计学意义。

结论

研究结果表明,在异位妊娠患者的治疗中,药物治疗和手术治疗的使用比例几乎相同(分别为48%和52%)。此外,研究表明单剂量甲氨蝶呤治疗比两剂量更成功。然而,在三种治疗方式中,手术治疗的成功率最高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e45e/11469796/81a76c3e2d92/cureus-0016-00000069216-i01.jpg

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