Thibault M, Blanchard G, Martres P
Laboratoire de bactériologie-virologie-hygiène, centre hospitalier René-Dubos, 6 avenue de l'Ile-de-France, 95301 Pontoise, France.
Pathol Biol (Paris). 2005 Oct-Nov;53(8-9):463-5. doi: 10.1016/j.patbio.2005.08.002. Epub 2005 Sep 21.
In our French general hospital with 1000 hospitalization beds, a specific isolation for multiresistant bacteria colonized or infected patients was set up since 1998. To assess the impact of these recommendations, the rate of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia was calculated for each year since 1998. From 1998 to 2004, 493 cases of Staphylococcus aureus (SA) bacteremia occurred in our hospital: 319 strains were susceptible to methicillin and 174 were MRSA. During the 7 years period of our study, we observed a significant tendency for reduction in the number of bacteremia with MRSA strains (p=0.016). The significant decrease of the MRSA bacteremia between 1998 and 2004 was obtained through the cooperation between staff members, bacteriologists and hospital nosocomial infection committee members.
在我们这家拥有1000张住院床位的法国综合医院，自1998年起就为多重耐药菌定植或感染患者设立了专门的隔离措施。为评估这些建议的影响，计算了自1998年以来每年耐甲氧西林金黄色葡萄球菌（MRSA）和甲氧西林敏感金黄色葡萄球菌（MSSA）菌血症的发生率。1998年至2004年期间，我院共发生493例金黄色葡萄球菌（SA）菌血症病例：319株对甲氧西林敏感，174株为MRSA。在我们研究的7年期间，我们观察到MRSA菌株菌血症数量有显著下降趋势（p = 0.016）。1998年至2004年期间MRSA菌血症的显著减少是通过工作人员、细菌学家和医院医院感染委员会成员之间的合作实现的。
