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活体供体移植中的技术问题。

Technical problems in living donor transplantation.

作者信息

Berardinelli L

机构信息

U.O. Vascular Surgery and Kidney Transplantation, Policlinico University Hospital IRCCS, Milan, Italy.

出版信息

Transplant Proc. 2005 Jul-Aug;37(6):2449-50. doi: 10.1016/j.transproceed.2005.06.021.

Abstract

Inferior outcomes are generally described with grafts having multiple arteries or renovascular disease. A consecutive series of 261 living donor (LD) transplants performed in the CsA era was classified in three groups with regard to the graft arterial abnormalities and the techniques employed for revascularization. Two hundred eleven recipients had a kidney with one "healthy" renal artery (Group I); 11 patients, multiple arteries, which were reconstructed by various intracorporeal techniques (Group II); 39 patients, one diseased renal artery or multiple arteries, which were reconstructed on the bench (Group III). One- and 3-year graft survivals not censored for death, were 91%, 82%, 100% and 87%, 82%, 100%, respectively, for Group I, Group II, and Group III. An aggressive policy in performing microsurgical bench reconstruction, also for kidneys with one artery that are affected by intrinsic disease, allowed us to obtain a 3-year graft survival of 100% in our more recent consecutive series of 53 LD transplants.

摘要

移植物存在多条动脉或肾血管疾病时,通常预后较差。在环孢素A时代进行的连续261例活体供肾(LD)移植,根据移植物动脉异常情况和血管重建所采用的技术分为三组。211例受者的供肾有一条“健康”肾动脉(第一组);11例受者的供肾有多条动脉,采用各种体内技术进行重建(第二组);39例受者的供肾有一条病变肾动脉或多条动脉,在体外工作台进行重建(第三组)。第一组、第二组和第三组未因死亡而截尾的1年和3年移植物存活率分别为91%、82%、100%和87%、82%、100%。在我们最近连续进行的53例LD移植中,对受内在疾病影响的单动脉肾也采取积极的显微外科体外工作台重建策略,使我们获得了100%的3年移植物存活率。

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