Köpf-Maier P, Leitner M, Voigtländer R, Köpf H
Z Naturforsch C Biosci. 1979 Dec;34(12):1174-6.
The antitumor activity of molybdocene dichloride is tested against Ehrlich ascites tumor in CF1 mice. The application of 75 of 100 mg/kg 24 h after transplantation achieves 100% tumor inhibition until day 30. Following the d0 and d1 metallocene dichlorides of titanium and vanadium, molybdocene dichloride is the first analogous d2 system revealing similar antineoplastic properties.
测试二氯钼ocene对CF1小鼠艾氏腹水瘤的抗肿瘤活性。移植后24小时应用100mg/kg中的75mg,直到第30天可实现100%的肿瘤抑制。继钛和钒的茂金属二氯化物在第0天和第1天应用之后,二氯钼ocene是第一个显示出类似抗肿瘤特性的类似d2体系。