结核分枝杆菌临床分离株对加雷沙星和DA-7867的体外敏感性
In vitro susceptibility of Mycobacterium tuberculosis clinical isolates to garenoxacin and DA-7867.
作者信息
Vera-Cabrera Lucio, Castro-Garza Jorge, Rendon Adrian, Ocampo-Candiani Jorge, Welsh Oliverio, Choi Sung Hak, Blackwood Kym, Molina-Torres Carmen
机构信息
Servicio de Dermatología, Hospital Universitario, José E. González, Madero y Gonzalitos, Col. Mitras Centro, Monterrey, NL, México.
出版信息
Antimicrob Agents Chemother. 2005 Oct;49(10):4351-3. doi: 10.1128/AAC.49.10.4351-4353.2005.
Abstract
The in vitro activities of DA-7867, a novel oxazolidinone, and garenoxacin (BMS-284756) were compared to those of linezolid in 67 susceptible and drug-resistant clinical isolates of Mycobacterium tuberculosis. DA-7867 was the most active drug with an MIC(90) of 0.125 microg/ml, compared to the MIC(90)s of 4 microg/ml of garenoxacin and 2 microg/ml of linezolid.
摘要
将新型恶唑烷酮类药物DA-7867和加替沙星（BMS-284756）的体外活性与利奈唑胺针对67株结核分枝杆菌敏感及耐药临床分离株的活性进行了比较。DA-7867是活性最强的药物，其MIC（90）为0.125μg/ml，相比之下，加替沙星的MIC（90）为4μg/ml，利奈唑胺的MIC（90）为2μg/ml。
相似文献
1
In vitro susceptibility of Mycobacterium tuberculosis clinical isolates to garenoxacin and DA-7867.
Antimicrob Agents Chemother. 2005 Oct;49(10):4351-3. doi: 10.1128/AAC.49.10.4351-4353.2005.
2
In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis complex isolated in Taiwan over 10 years.
Antimicrob Agents Chemother. 2008 Jun;52(6):2226-7. doi: 10.1128/AAC.00414-07. Epub 2008 Apr 7.
3
In vitro activities of PNU-100480 and linezolid against drug-susceptible and drug-resistant Mycobacterium tuberculosis isolates.
Int J Antimicrob Agents. 2013 Jul;42(1):96-7. doi: 10.1016/j.ijantimicag.2013.03.002. Epub 2013 May 15.
4
[Effect of linezolid in combination with isoniazid and rifampicin against multidrug resistant Mycobacterium tuberculosis clinical isolates].
Mikrobiyol Bul. 2009 Apr;43(2):293-7.
5
First linezolid-resistant clinical isolates of Mycobacterium tuberculosis.
Antimicrob Agents Chemother. 2007 Apr;51(4):1534-6. doi: 10.1128/AAC.01113-06. Epub 2007 Jan 22.
6
In vitro activity of linezolid against Mycobacterium tuberculosis strains isoalted from Western Turkey.
Jpn J Infect Dis. 2009 Sep;62(5):384-5.
7
In vitro efficacy of Linezolid on clinical strains of Mycobacterium tuberculosis and other mycobacteria.
New Microbiol. 2006 Oct;29(4):275-80.
8
[Evaluation of the mycobacterium efficacy of linezolid in vitro].
Zhonghua Jie He He Hu Xi Za Zhi. 2011 Aug;34(8):575-8.
9
In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis that are susceptible or resistant to first-line antituberculous drugs.
Antimicrob Agents Chemother. 2003 Jan;47(1):416-7. doi: 10.1128/AAC.47.1.416-417.2003.
10
Post-antibiotic effects of linezolid and other agents against Mycobacterium tuberculosis.
Int J Antimicrob Agents. 2008 Apr;31(4):395-6. doi: 10.1016/j.ijantimicag.2007.12.002. Epub 2008 Feb 12.
引用本文的文献
1
Chemical Classes Presenting Novel Antituberculosis Agents Currently in Different Phases of Drug Development: A 2010-2020 Review.
Pharmaceuticals (Basel). 2021 May 13;14(5):461. doi: 10.3390/ph14050461.
2
The Sterilizing Effect of Intermittent Tedizolid for Pulmonary Tuberculosis.
Clin Infect Dis. 2018 Nov 28;67(suppl_3):S336-S341. doi: 10.1093/cid/ciy626.
3
Multiparameter Responses to Tedizolid Monotherapy and Moxifloxacin Combination Therapy Models of Children With Intracellular Tuberculosis.
Clin Infect Dis. 2018 Nov 28;67(suppl_3):S342-S348. doi: 10.1093/cid/ciy612.
4
Current development and future prospects in chemotherapy of tuberculosis.
Respirology. 2010 Jul;15(5):764-78. doi: 10.1111/j.1440-1843.2010.01775.x. Epub 2010 Jun 4.
5
Promising antituberculosis activity of the oxazolidinone PNU-100480 relative to that of linezolid in a murine model.
Antimicrob Agents Chemother. 2009 Apr;53(4):1314-9. doi: 10.1128/AAC.01182-08. Epub 2008 Dec 15.
6
Therapeutic effect of a novel oxazolidinone, DA-7867, in BALB/c mice infected with Nocardia brasiliensis.
PLoS Negl Trop Dis. 2008 Sep 10;2(9):e289. doi: 10.1371/journal.pntd.0000289.
7
Prodrugs for the treatment of neglected diseases.
Molecules. 2007 Mar 19;13(3):616-77. doi: 10.3390/molecules13030616.
8
In vitro activities of DA-7157 and DA-7218 against Mycobacterium tuberculosis and Nocardia brasiliensis.
Antimicrob Agents Chemother. 2006 Sep;50(9):3170-2. doi: 10.1128/AAC.00571-06.
本文引用的文献
1
A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis.
Science. 2005 Jan 14;307(5707):223-7. doi: 10.1126/science.1106753. Epub 2004 Dec 9.
2
Mycobacterium tuberculosis DNA gyrase: interaction with quinolones and correlation with antimycobacterial drug activity.
Antimicrob Agents Chemother. 2004 Apr;48(4):1281-8. doi: 10.1128/AAC.48.4.1281-1288.2004.
3
In vitro activities of new antimicrobials against Nocardia brasiliensis.
Antimicrob Agents Chemother. 2004 Feb;48(2):602-4. doi: 10.1128/AAC.48.2.602-604.2004.
4
In vitro activities of DA-7867, a novel oxazolidinone, against recent clinical isolates of aerobic and anaerobic bacteria.
Antimicrob Agents Chemother. 2004 Jan;48(1):352-7. doi: 10.1128/AAC.48.1.352-357.2004.
5
The global situation of MDR-TB.
Tuberculosis (Edinb). 2003;83(1-3):44-51. doi: 10.1016/s1472-9792(02)00058-6.
6
The TB epidemic from 1992 to 2002.
Tuberculosis (Edinb). 2003;83(1-3):4-14. doi: 10.1016/s1472-9792(02)00071-9.
7
In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis that are susceptible or resistant to first-line antituberculous drugs.
Antimicrob Agents Chemother. 2003 Jan;47(1):416-7. doi: 10.1128/AAC.47.1.416-417.2003.
8
In vitro activity of moxifloxacin, levofloxacin, gatifloxacin and linezolid against Mycobacterium tuberculosis.
Int J Antimicrob Agents. 2002 Dec;20(6):464-7. doi: 10.1016/s0924-8579(02)00239-x.
9
Activities of several novel oxazolidinones against Mycobacterium tuberculosis in a murine model.
Antimicrob Agents Chemother. 1999 May;43(5):1189-91. doi: 10.1128/AAC.43.5.1189.
10
Rapid, low-technology MIC determination with clinical Mycobacterium tuberculosis isolates by using the microplate Alamar Blue assay.
J Clin Microbiol. 1998 Feb;36(2):362-6. doi: 10.1128/JCM.36.2.362-366.1998.
Zotero 插件