Voon Wen-Chol, Su Ho-Ming, Yen Hsueh-Wei, Lin Tsung-Hsien, Lai Wen-Ter, Sheu Sheng-Hsiung
Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University, Taiwan, Republic of China.
Echocardiography. 2005 Oct;22(9):730-5. doi: 10.1111/j.1540-8175.2005.00126.x.
It is still unknown whether a correlation exists between left ventricular Tei index obtained by tissue Doppler imaging and that determined by flow Doppler waveforms. This study was conducted to evaluate their relationship and to assess the positional effect on them.
Twenty-six healthy subjects and 25 patients with essential hypertension were included. On the tissue Doppler images, the time interval from the end to the onset of the mitral annular velocity pattern during diastole and the duration of the S-wave were used to calculate tissue Doppler Tei index.
The tissue Doppler Tei index correlated with the flow Doppler Tei index at sitting position (r = 0.406, P = 0.003), but not at left lateral decubitus position. The limits of agreement for the Tei index measured by both methods were -0.26 to 0.62 at left lateral decubitus position and -0.09 to 0.55 at sitting position. Preload reduction associated with sitting position with dangling feet raised the Tei index both in the healthy controls [0.54 (0.14) vs 0.42 (0.12), P < 0.001] and in the hypertensives [0.53 (0.15) vs 0.46 (0.12), P = 0.005]. There was a similar positional effect on the tissue Doppler Tei index in the control subjects [0.75 (0.12) vs 0.53 (0.10), P < 0.001].
Tissue Doppler Tei index does not seem to be a suitable substitute for flow Doppler Tei index. Flow Doppler Tei index is preload dependent and the loading status should be taken into consideration at the application of Tei index to the evaluation of myocardial performance.
通过组织多普勒成像获得的左心室Tei指数与通过血流多普勒波形测定的左心室Tei指数之间是否存在相关性尚不清楚。本研究旨在评估它们之间的关系,并评估体位对它们的影响。
纳入26名健康受试者和25名原发性高血压患者。在组织多普勒图像上,利用舒张期二尖瓣环速度模式结束至开始的时间间隔和S波持续时间计算组织多普勒Tei指数。
组织多普勒Tei指数与坐位时的血流多普勒Tei指数相关(r = 0.406,P = 0.003),但与左侧卧位时不相关。两种方法测量的Tei指数的一致性界限在左侧卧位时为-0.26至0.62,在坐位时为-0.09至0.55。坐位且双脚悬空导致的前负荷降低使健康对照组[0.54(0.14)对0.42(0.12),P < 0.001]和高血压患者[0.53(0.15)对0.46(0.12),P = 0.005]的Tei指数均升高。对照组中,体位对组织多普勒Tei指数也有类似影响[0.75(0.12)对0.53(0.10),P < 0.001]。
组织多普勒Tei指数似乎不是血流多普勒Tei指数的合适替代指标。血流多普勒Tei指数依赖于前负荷,在应用Tei指数评估心肌功能时应考虑负荷状态。