Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Korean Circ J. 2010 Aug;40(8):391-8. doi: 10.4070/kcj.2010.40.8.391. Epub 2010 Aug 31.
The reliability and usefulness of the right ventricular (RV) Tei index (RTX) remains controversial because it has not been possible to simultaneously measure RV inflow and outflow. However, dual pulsed-wave Doppler (DPD) enables flow velocities to be obtained at different sampling sites simultaneously. In this study we evaluated the feasibility and reliability of RTX values obtained by DPD (RTX(DPD)).
Forty-one patients who underwent cardiac catheterization and echocardiography for RV volume or pressure overloading conditions were evaluated. Symptom-limited exercise treadmill testing with expired gas analysis was performed and maximal exercise capacity was measured.
RTX by conventional flow Doppler (RTX(CFD), 0.262±0.164) was similar to RTX(DPD) (0.253±0.117, p=NS), whereas RTX by tissue Doppler echocardiography (RTX(TDE), 0.447±0.125) was significantly larger than RTX(DPD) (p<0.001). Based on multiple regression analysis, maximal exercise capacity was independently related to RTX(DPD) (β=-0.60, p<0.001), mid-RV dimension (β=-0.26, p=0.012), left ventricular ejection fraction (β=0.22, p=0.023), and early diastolic tricuspid annular velocity (β=0.21, p=0.048).
It is feasible and reliable to evaluate RV function using RTX(DPD) values. However, to evaluate the clinical usefulness of RTX(DPD), additional studies are required with a large number of patients and long-term follow-up.
由于无法同时测量右心室(RV)流入和流出,右心室(RV)Tei 指数(RTX)的可靠性和实用性仍存在争议。然而,双脉冲波多普勒(DPD)可同时在不同取样点获得流速。本研究旨在评估 DPD 测量的 RV 功能指数(RTX(DPD))的可行性和可靠性。
对 41 例因 RV 容量或压力超负荷而行心导管检查和超声心动图检查的患者进行了评估。对患者进行了症状限制的踏车运动试验和呼气末气体分析,以测量最大运动能力。
传统血流多普勒(RTX(CFD),0.262±0.164)与 DPD(RTX(DPD),0.253±0.117)相似(p=NS),而组织多普勒超声心动图(RTX(TDE),0.447±0.125)显著大于 DPD(p<0.001)。多元回归分析显示,最大运动能力与 RTX(DPD)(β=-0.60,p<0.001)、RV 中部内径(β=-0.26,p=0.012)、左心室射血分数(β=0.22,p=0.023)和舒张早期三尖瓣环速度(β=0.21,p=0.048)独立相关。
使用 RTX(DPD)值评估 RV 功能是可行且可靠的。然而,为了评估 RTX(DPD)的临床实用性,还需要进行更多的研究,纳入更多的患者并进行长期随访。