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人类内侧颞叶对感知的贡献:弥合动物研究与人类研究之间的差距。

The contribution of the human medial temporal lobe to perception: bridging the gap between animal and human studies.

作者信息

Lee Andy C H, Barense Morgan D, Graham Kim S

机构信息

MRC Cognition and Brain Sciences Unit, Cambridge, UK.

出版信息

Q J Exp Psychol B. 2005 Jul-Oct;58(3-4):300-25. doi: 10.1080/02724990444000168.

DOI:10.1080/02724990444000168
PMID:16194971
Abstract

The medial temporal lobe (MTL) has been considered traditionally to subserve declarative memory processes only. Recent studies in nonhuman primates suggest, however, that the MTL may also be critical to higher order perceptual processes, with the hippocampus and perirhinal cortex being involved in scene and object perception, respectively. The current article reviews the human neuropsychological literature to determine whether there is any evidence to suggest that these same views may apply to the human MTL. Although the majority of existing studies report intact perception following MTL damage in human amnesics, there have been recent studies that suggest that when scene and object perception are assessed systematically, significant impairments in perception become apparent. These findings have important implications for current mnemonic theories of human MTL function and our understanding of human amnesia as a result of MTL lesions.

摘要

传统上认为内侧颞叶(MTL)仅参与陈述性记忆过程。然而,最近对非人类灵长类动物的研究表明,MTL对高阶感知过程可能也至关重要,其中海马体和嗅周皮质分别参与场景和物体感知。本文回顾了人类神经心理学文献,以确定是否有证据表明这些相同观点也适用于人类MTL。尽管大多数现有研究报告称,人类失忆症患者MTL受损后感知功能完好,但最近有研究表明,当系统评估场景和物体感知时,感知功能会出现明显损伤。这些发现对当前关于人类MTL功能的记忆理论以及我们对MTL损伤导致的人类失忆症的理解具有重要意义。

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The contribution of the human medial temporal lobe to perception: bridging the gap between animal and human studies.人类内侧颞叶对感知的贡献:弥合动物研究与人类研究之间的差距。
Q J Exp Psychol B. 2005 Jul-Oct;58(3-4):300-25. doi: 10.1080/02724990444000168.
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Perceptual deficits in amnesia: challenging the medial temporal lobe 'mnemonic' view.失忆症中的感知缺陷:挑战内侧颞叶的“记忆”观点。
Neuropsychologia. 2005;43(1):1-11. doi: 10.1016/j.neuropsychologia.2004.07.017.
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The role of the perirhinal cortex and hippocampus in learning, memory, and perception.嗅周皮质和海马体在学习、记忆及感知中的作用。
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Perception and the medial temporal lobe: evaluating the current evidence.感知与内侧颞叶:评估当前证据
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Object memory and perception in the medial temporal lobe: an alternative approach.内侧颞叶中的客体记忆与感知:一种替代方法
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The perceptual-mnemonic/feature conjunction model of perirhinal cortex function.嗅周皮质功能的感知记忆/特征联结模型
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Untangling memory from perception in the medial temporal lobe.解开内侧颞叶中记忆与感知的纠缠。
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The role of the human medial temporal lobe in object recognition and object discrimination.人类内侧颞叶在物体识别和物体辨别中的作用。
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Spared perception of object geometry and object components after hippocampal damage.海马体损伤后对物体几何形状和物体组成部分的保留感知。
Learn Mem. 2018 Jun 15;25(7):330-334. doi: 10.1101/lm.047464.118. Print 2018 Jul.
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Encoding-related brain activity and accelerated forgetting in transient epileptic amnesia.
短暂性癫痫性遗忘症中的与编码相关的大脑活动和加速遗忘。
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Viewpoints: how the hippocampus contributes to memory, navigation and cognition.观点:海马体如何影响记忆、导航和认知。
Nat Neurosci. 2017 Oct 26;20(11):1434-1447. doi: 10.1038/nn.4661.
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Representational specializations of the hippocampus in phylogenetic perspective.从系统发育角度看海马体的表征特化。
Neurosci Lett. 2018 Jul 27;680:4-12. doi: 10.1016/j.neulet.2017.04.065. Epub 2017 May 1.
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Deciding what is possible and impossible following hippocampal damage in humans.判定人类海马体损伤后哪些情况可能发生、哪些不可能发生。
Hippocampus. 2017 Mar;27(3):303-314. doi: 10.1002/hipo.22694. Epub 2017 Jan 7.
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Super-Memorizers Are Not Super-Recognizers.超级记忆者并非超级识别者。
PLoS One. 2016 Mar 23;11(3):e0150972. doi: 10.1371/journal.pone.0150972. eCollection 2016.
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Anterior hippocampus: the anatomy of perception, imagination and episodic memory.前海马体:感知、想象与情景记忆的解剖结构
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