Urgolites Zhisen J, Levy Daniel A, Hopkins Ramona O, Squire Larry R
Veterans Affairs San Diego Healthcare System, San Diego, California 92161, USA.
Department of Psychiatry, University of California, San Diego, La Jolla, California 92093, USA.
Learn Mem. 2018 Jun 15;25(7):330-334. doi: 10.1101/lm.047464.118. Print 2018 Jul.
We tested the proposal that medial temporal lobe (MTL) structures support not just memory but also high-level object perception. In one task, participants decided whether a line drawing could represent an object in three-dimensional space and, in another task, they saw the components of an object and decided what object could be formed if the components were assembled. Patients with hippocampal lesions were intact, indicating that the hippocampus is not needed for perceiving the structural coherence of objects or appreciating the relations among object parts. Patients with large MTL lesions were moderately impaired, likely due to damage outside the MTL.
我们测试了这样一种观点，即内侧颞叶（MTL）结构不仅支持记忆，还支持高级物体感知。在一项任务中，参与者判断一幅线条画是否能代表三维空间中的一个物体，在另一项任务中，他们看到一个物体的组成部分，并判断如果将这些组成部分组装起来可以形成什么物体。海马体受损的患者表现正常，这表明感知物体的结构连贯性或理解物体各部分之间的关系并不需要海马体。患有大面积MTL损伤的患者有中度损伤，可能是由于MTL以外的损伤。
