van den Brink Carolien L, Tijhuis Marja, van den Bos Geertrudis A M, Giampaoli Simona, Nissinen Aulikki, Kromhout Daan
National Institute for Public Health and the Environment, Center for Prevention and Health Services Research, PO Box 1, 3720 BA Bilthoven, The Netherlands.
Am J Public Health. 2005 Nov;95(11):2029-34. doi: 10.2105/AJPH.2004.050914. Epub 2005 Sep 29.
To investigate the effect of disability severity and the contribution of self-rated health and depressive symptoms to 10-year mortality.
Longitudinal data were collected from 1141 men aged 70 to 89 years from the Finland, Italy, and the Netherlands Elderly Study from 1990 to 2000. Disability severity was classified into 4 categories: no disability, instrumental activities, mobility, and basic activities of daily living. Self-rated health and depressive symptoms were classified into 2 and 3 categories, respectively. Multivariate Cox proportional hazard models were used to calculate mortality risks.
Men with severe disability had a risk of mortality that was more than 2-fold higher (hazard ratio [HR]=2.41; 95% confidence interval [CI]=1.84, 3.16) than that of men without disability. Men who had severe disability and did not feel healthy had the highest mortality risk (HR = 3.30; 95% CI = 2.52, 4.33). This risk was lower at lower levels of disability and higher levels of self-rated health. The same trend was observed for depressive symptoms.
For adequate prognoses on mortality or for developing intervention strategies, not only physical aspects of health but also other health outcomes should be taken into account.
探讨残疾严重程度以及自评健康状况和抑郁症状对10年死亡率的影响。
从1990年至2000年芬兰、意大利和荷兰老年研究中收集了1141名70至89岁男性的纵向数据。残疾严重程度分为4类:无残疾、工具性活动、行动能力和日常生活基本活动。自评健康状况和抑郁症状分别分为2类和3类。采用多变量Cox比例风险模型计算死亡风险。
重度残疾男性的死亡风险比无残疾男性高出2倍多(风险比[HR]=2.41;95%置信区间[CI]=1.84, 3.16)。重度残疾且感觉不健康的男性死亡风险最高(HR = 3.30;95% CI = 2.52, 4.33)。在残疾程度较低和自评健康状况较高时,这种风险较低。抑郁症状也观察到相同趋势。
为了对死亡率进行充分的预后评估或制定干预策略,不仅应考虑健康的身体方面,还应考虑其他健康结果。