Bergland Astrid, Jørgensen Lone, Emaus Nina, Strand Bjørn Heine
Department of Physiotherapy, Oslo and Akershus University College of Applied Sciences, Faculty of Health Sciences, Pilestredet, P.O. Box 4 St. Olavs plass, 0130, Oslo, Norway.
Department of Health and Care Sciences, UiT The Arctic University of Norway, 9037, Tromsø, Norway.
BMC Health Serv Res. 2017 Jan 10;17(1):22. doi: 10.1186/s12913-016-1950-0.
Disability in older adults is associated with loss of independence, institutionalization, and death. The aim of this study was to study the association between the Timed Up and Go (TUG) test and all-cause mortality in a population-based sample of older men and women.
Our study population was home dwellers aged 65 and above, who participated in the fifth wave of the Tromsø study. This study included the TUG test and a range of lifestyle and mortality predictors. Participants were linked to the Cause of Death Registry and followed up for mortality for a maximum of 11.8 years. Cox regression was used to investigate the association between TUG and total mortality.
Mean TUG score was 12.6 s, and men performed better than women. The oldest participants had poorer TUG score compared to younger participants, increasing 0.25 s per year. There was a significant association between TUG and all-cause mortality, and the association was equally strong in men and women. Across the TUG-score categories, from quickest fifth to slowest fifth, the mortality increased in a step-wise fashion. Compared to the quickest fifth, the slowest fifth had hazard ratio (HR) of 1.79 (95% confidence interval (CI) 1.33, 2.42) in a model adjusted for age and gender. For each standard deviation TUG-score the increase in HR was 1.23 (95% CI 1.14, 1.33). The association between the TUG score and mortality remained significant after adjusting for self-reported health, body mass index, smoking and education.
A significant association between the TUG score and mortality was observed in both men and women. Identifying older people with poor TUG may aid in identifying those at risk and thus targeted interventions may be applied.
老年人的残疾与失去独立生活能力、入住养老机构及死亡相关。本研究旨在探讨在以社区为基础的老年男性和女性样本中，定时起立行走（TUG）测试与全因死亡率之间的关联。
我们的研究对象为65岁及以上的居家老人，他们参与了特罗姆瑟研究的第五轮调查。该研究包括TUG测试以及一系列生活方式和死亡率预测因素。参与者与死亡原因登记处建立了联系，并对其死亡率进行了长达11.8年的随访。采用Cox回归分析来研究TUG与总死亡率之间的关联。
TUG平均得分为12.6秒，男性表现优于女性。与年轻参与者相比，年龄最大的参与者TUG得分较差，每年增加0.25秒。TUG与全因死亡率之间存在显著关联，且在男性和女性中关联强度相同。在TUG得分类别中，从最快的五分之一到最慢的五分之一，死亡率呈逐步上升趋势。在调整了年龄和性别的模型中，与最快的五分之一相比，最慢的五分之一的风险比（HR）为1.79（95%置信区间（CI）1.33，2.42）。TUG得分每增加一个标准差，HR增加1.23（95%CI 1.14，1.33）。在调整了自我报告的健康状况、体重指数、吸烟和教育程度后，TUG得分与死亡率之间的关联仍然显著。
在男性和女性中均观察到TUG得分与死亡率之间存在显著关联。识别TUG得分较差的老年人可能有助于识别高危人群，从而可以采取针对性的干预措施。
