Downing G J, Vandenboom E, Thorp J A
Department of Pediatrics, University of Missouri-Kansas City.
J Reprod Med. 1992 Jun;37(6):566-8.
Clinical recognition of antepartum fetomaternal hemorrhage (FMH) is most often achieved by the observation of characteristic fetal heart rate (FHR) patterns and positive Kleihauer-Betke acid elution staining. Both methods are noted to lack sensitivity and specificity. A case of suspected antepartum FMH occurred with intermittent sinusoidal FHR tracings. Fetal blood sampling by cordocentesis in situations with equivocal antenatal testing, such as in this case, allows not only confirmation of fetal anemia but assessment of fetal acid-base status. In pregnancies of less than 32 weeks' gestation complicated by severe antepartum FMH, intravascular transfusion may be offered via this technique. Cordocentesis is beneficial in the management of pregnancies with uncertain FHR patterns when antepartum FMH is suspected.
产前胎儿-母体出血(FMH)的临床诊断通常是通过观察特征性的胎儿心率(FHR)模式以及Kleihauer-Betke酸洗脱染色呈阳性来实现的。但这两种方法都缺乏敏感性和特异性。有一例疑似产前FMH的病例出现了间歇性正弦波FHR描记图。在产前检查结果不明确的情况下,如本病例,通过脐静脉穿刺进行胎儿血样采集,不仅可以确认胎儿贫血,还能评估胎儿的酸碱状态。对于妊娠小于32周且并发严重产前FMH的孕妇,可通过该技术进行血管内输血。当怀疑产前FMH且FHR模式不确定时,脐静脉穿刺有助于妊娠的管理。