Gudinaviciene Inga, Pranys Darius, Zheng Pinping, Kros Johan M
Brain Pathol. 2005 Jul;15(3):263-4, 267. doi: 10.1111/j.1750-3639.2005.tb00530.x.
February 2005. Case report of a 10-month-old boy with a large tumor located in the pineal gland, consisting of glia, ganglion cells, pigmented neuroepithelium and striated muscle, without immature components. The combination of neuroectodermal and mesenchymal constituents includes entities as pineal anlage tumor (melanotic neuroectodermal tumor of infancy, MNTI), ectomesenchymoma, medullomyoblastoma, and teratoma in the differential diagnosis. Lack of immature elements in this case, however, eliminates ectomesenchymoma and medullomyoblastoma from the differential diagnosis. Retinal anlage tumors, to be considered as MNTI at the site of the pineal gland, usually harbor immature components as well. Therefore, the present case does not match strict criteria of any of the categories mentioned and therefore we have designated it as a "pineal anlage tumor (without immature components)".
2005年2月。一名10个月大男童的病例报告,其松果体区有一个巨大肿瘤,由神经胶质、神经节细胞、色素性神经上皮和横纹肌组成,无不成熟成分。神经外胚层和间充质成分的组合在鉴别诊断中包括松果体原基肿瘤(婴儿黑色素性神经外胚层肿瘤,MNTI)、外间充质瘤、髓母细胞瘤和畸胎瘤。然而,该病例缺乏不成熟成分,在鉴别诊断中排除了外间充质瘤和髓母细胞瘤。松果体区的视网膜原基肿瘤通常也含有不成熟成分,因此被视为MNTI。因此,本病例不符合上述任何一类的严格标准,故我们将其命名为“松果体原基肿瘤(无不成熟成分)”。