Bittinger A, Rossberg C, Rodehüser M
Department of Pathology, Philipps-University Marburg, Germany.
Gen Diagn Pathol. 1997 Feb;142(3-4):221-5.
Malignant ectomesenchymoma is a rare soft tissue tumor of the childhood believed to arise from a remnant of pluripotential migratory neural crest cell (ectomesenchym) and composed of both a mesenchymal element (most often embryonal rhabdomyosarcoma) and a neuroectodermal element (ganglioneuroma, schwanomma neuroblastoma or melanocytic cells). Reported sites of origin are the abdomen, perineum or scrotum, the extremities, the middle ear, nasopharynx, face, and neck. Herein we report a new case of an orbital ectomesenchymoma studied by means of histochemistry and immunohistochemistry in order to increase the morphologic and histogenetic knowledge of this peculiar tumor and its significance concerning the differential diagnosis.
恶性外胚层间叶瘤是一种罕见的儿童软组织肿瘤，被认为起源于多能迁移神经嵴细胞（外胚层间叶组织）的残余物，由间叶成分（最常见的是胚胎性横纹肌肉瘤）和神经外胚层成分（神经节神经瘤、神经鞘瘤、神经母细胞瘤或黑素细胞）组成。报道的起源部位有腹部、会阴或阴囊、四肢、中耳、鼻咽、面部和颈部。在此，我们报告一例眼眶外胚层间叶瘤的新病例，通过组织化学和免疫组织化学方法进行研究，以增加对这种特殊肿瘤的形态学和组织发生学的认识及其在鉴别诊断中的意义。
