Tornvall Per, Nilsson Tage, Jensen Jens
Hjärtkliniken, Karolinska Universitetssjukhuset Solna, Stockholm, Sweden.
Lakartidningen. 2005;102(36):2478-81.
The technique of Percutaneous Coronary Intervention (PCI) has improved considerably over the last decades. Important developments have been the introduction of stents and better anticoagulation treatment. PCI is used most commonly in the treatment of unstable angina pectoris or non ST-elevation myocardial infarction. In Sweden today, more than half of the patients with ST-elevation myocardial infarction are treated primarily with PCI. Despite the high degree of opening of the infarct-related artery, the reduction in mortality is modest compared with treatment with thrombolysis indicating that there is room for considerable improvement. There is a need for randomised studies of adjunctive therapies but it can be speculated that thrombectomy devices and specific reperfusion injury therapy might reduce mortality in PCI treatment of ST-elevation myocardial infarction.
在过去几十年中，经皮冠状动脉介入治疗（PCI）技术有了显著进步。重要进展包括支架的引入和更好的抗凝治疗。PCI最常用于治疗不稳定型心绞痛或非ST段抬高型心肌梗死。在当今瑞典，超过一半的ST段抬高型心肌梗死患者首先接受PCI治疗。尽管梗死相关动脉开通程度很高，但与溶栓治疗相比，死亡率降低幅度不大，这表明仍有很大的改进空间。需要对辅助治疗进行随机研究，但可以推测，血栓切除术装置和特定的再灌注损伤治疗可能会降低ST段抬高型心肌梗死PCI治疗的死亡率。
