Mimori Y, Tanaka H
Third Dept. of Internal Medicine, Hiroshima University School of Medicine.
Nihon Rinsho. 1992 Apr;50(4):753-8.
The sympathetic skin response (SSR) is a slow wave resulting from activation of the sudomotor sympathetic efferent fibers. Records are usually made with surface electrodes on hand or foot after the electrical stimulation. Either the amplitude or the latency of the response varies greatly on consecutive stimulations and there is also a remarkable tendency to habituation. Therefore SSR is considered abnormal if no significant responses are detected. SSR is well correlated with other autonomic function tests and its abnormality is documented in a variety of neurologic disorders such as diabetic neuropathy, cerebrovascular disease and Parkinson's disease. In good methodological conditions, SSR is a simple, reliable indicator of sympathetic sudomotor outflow in central and peripheral nervous system disorders.
交感神经皮肤反应（SSR）是由发汗运动交感传出纤维激活产生的慢波。通常在电刺激后，使用表面电极在手部或足部进行记录。连续刺激时，反应的幅度或潜伏期变化很大，并且还有明显的习惯化倾向。因此，如果未检测到明显反应，则认为SSR异常。SSR与其他自主神经功能测试密切相关，其异常在多种神经系统疾病中都有记录，如糖尿病性神经病变、脑血管疾病和帕金森病。在良好的方法学条件下，SSR是中枢和周围神经系统疾病中交感神经发汗运动传出功能的简单、可靠指标。
