Vasconcelos Maria P, Jorge Zulmira, Nobre Ema L, Domingues Andreia, Macedo Ana, Castro J Jácome de
Serviço de Endocrinologia, Diabetes e Metabolismo, Hospital Militar Principal, Lisboa.
Acta Med Port. 2004 Sep-Oct;17(5):359-66. Epub 2004 Dec 20.
Slight weight losses (5%) are consensually accepted as important in the treatment of obesity today. Some authors also consider that maintaining weight is an indicator of success in the treatment of this condition.
Characterisation and assessment of changes in weight in obese patients monitored at an obesity clinic in a hospital endocrinology department.
Retrospective analysis of the clinical files of the Endocrinology Clinic. The patients included were overweight adults (BMI = 25 kg/m2) who had been monitored since 1999 and were not suffering from thyroid dysfunction or hypercortisolism. Data were gathered on bio-demographic and anthropometric characteristics, reason for consultation, type of treatment, results achieved and dropouts. The statistical analysis included calculating central tendency measures and dispersion for the continuous variables and building frequency tables to describe the categorical variables. We used the t-test to compare average values between samples. Frequencies were compared by means of the chi-squared test or Fisher's exact test. The significance level was 5%.
We studied 457 patients (60.6% female) with an average age of 53 years (DP +/- 15) and an average BMI of 32.4 +/- 5.1 Kg/m2. 51.9% of the patients came to the clinic because of overweight (n = 237) (Obesity Group-OBG), while the rest did so because of diabetes mellitus (35.4%) or some other disease (12.7%) (Other Cause Group-OCG). A dietary plan was prescribed for 86.1% (OBG) and 81.8% (OCG), drugs for 16.9% (OBG) and 6.4% (OCG) and physical activity for 77.6% (OBG) and 77.7% (OCG). The average weight loss was 2.1% in the OBG. The individuals who dropped out of the clinic had lost less weight (1.3% vs. 2.9%), although the difference was not significant. More than half (57.7%) of the individuals studied lost weight, 14.4% remained the same and 27.8% gained weight.
目前普遍认为，轻度体重减轻（5%）对肥胖症治疗具有重要意义。一些作者还认为，维持体重是该疾病治疗成功的一个指标。
对一家医院内分泌科肥胖门诊监测的肥胖患者体重变化进行特征描述和评估。
对内分泌门诊的临床档案进行回顾性分析。纳入的患者为超重成年人（BMI = 25 kg/m²），自1999年起接受监测，且未患有甲状腺功能障碍或皮质醇增多症。收集了生物人口统计学和人体测量学特征、就诊原因、治疗类型、取得的结果及退出情况等数据。统计分析包括计算连续变量的集中趋势指标和离散指标，以及构建频率表来描述分类变量。我们使用t检验比较样本间的平均值。通过卡方检验或费舍尔精确检验比较频率。显著性水平为5%。
我们研究了457例患者（女性占60.6%），平均年龄53岁（标准差±15），平均BMI为32.4±5.1 Kg/m²。51.9%的患者因超重前来门诊（n = 237）（肥胖组 - OBG），其余患者因糖尿病（35.4%）或其他疾病（12.7%）前来就诊（其他病因组 - OCG）。86.1%的OBG患者和81.8%的OCG患者被开具了饮食计划，16.9%的OBG患者和6.4%的OCG患者使用了药物，77.6%的OBG患者和77.7%的OCG患者进行了体育锻炼。OBG患者的平均体重减轻了2.1%。退出门诊的患者体重减轻较少（1.3%对2.9%），尽管差异不显著。超过一半（57.7%）的研究对象体重减轻，14.4%体重保持不变，27.8%体重增加。
1）只有50%的超重患者前来我院减重。2）超过75%的超重患者，无论其首次就诊原因如何，都有一份规定的结构化饮食计划。3）约75%的患者达到了可接受的目标（维持体重或减重），其中25%的患者体重减轻超过初始体重的5%。
