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脊髓损伤后的男性生育能力与性功能

Male fertility and sexual function after spinal cord injury.

作者信息

Brown D J, Hill S T, Baker H W G

机构信息

Victorian Spinal Cord Service, Austin Health, Heidelberg, Vic., Australia.

出版信息

Prog Brain Res. 2006;152:427-39. doi: 10.1016/S0079-6123(05)52029-6.

Abstract

Spinal cord injury has an enormous impact upon the sexual relationship of a man and his partner. Erection may be partial or absent, orgasm altered or impossible, and fertility severely impaired. New understanding of the physiology of sexual function and improved treatment can enable most cord-injured men to achieve erections suitable for sexual satisfaction. Modern methods of sperm collection and fertility treatment mean that many can also be fathers. The best results are obtained by a team approach involving rehabilitation and reproductive medicine clinicians, nurses, spinal cord injury specialists and counselors with the cord-injured man and his partner. Erections can be achieved by drugs, such as sildenafil, that block phosphodiesterase 5, prolonging the action of nitric oxide with resultant smooth muscle relaxation. Intracavernosal prostaglandin E1 and mechanical systems, such as vacuum pumps and constriction rings, are also effective. Sexual gratification can be promoted in the context of an understanding relationship in which the cord-injured person can gain pleasure from pleasing his partner and also from his partner's exploration of erotogenic areas not affected by the spinal cord injury. An emphasis on the broader view of sexuality in relationships allows for a continuance and strengthening of bonds between the couple. Vibration ejaculation or electroejaculation can be used to collect semen. For a limited period in the acute phase, usually for about 6-12 days after injury, normal semen can be obtained by electroejaculation from some cord-injured men. With chronic spinal cord injury the semen is of variable quality. Some patients have necrospermia, which may be improved by regular ejaculation. Others have poor quality semen or spermatogenic disorders and, in this situation, in vitro fertilization techniques must be used to achieve parenthood. Trials of assisted ejaculation help individualize cost-effective management of the infertility.

摘要

脊髓损伤对男性及其伴侣的性关系有巨大影响。勃起可能部分存在或完全缺失,性高潮改变或无法达到,生育能力严重受损。对性功能生理学的新认识和改进的治疗方法使大多数脊髓损伤男性能够实现适合性满足的勃起。现代精子采集和生育治疗方法意味着许多人也可以成为父亲。通过由康复和生殖医学临床医生、护士、脊髓损伤专家以及顾问组成的团队方法,并让脊髓损伤男性及其伴侣参与其中,可获得最佳效果。勃起可通过药物实现,如西地那非,它能阻断磷酸二酯酶5,延长一氧化氮的作用,从而使平滑肌松弛。海绵体内注射前列腺素E1以及机械装置,如真空泵和缩窄环,也有效。在相互理解的关系中可促进性满足,在这种关系中,脊髓损伤者能从取悦伴侣以及伴侣对未受脊髓损伤影响的性敏感区域的探索中获得乐趣。强调性关系中更广泛的性观念有助于夫妻之间关系的延续和加强。振动射精或电射精可用于采集精液。在急性期的有限时间段内,通常是受伤后约6 - 12天,一些脊髓损伤男性可通过电射精获得正常精液。对于慢性脊髓损伤患者,精液质量参差不齐。一些患者有死精症,定期射精可能会有所改善。另一些患者精液质量差或有生精障碍,在这种情况下,必须采用体外受精技术来实现生育。辅助射精试验有助于对不育症进行个性化的经济有效管理。

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