Johnson Jeffrey G, First Michael B, Cohen Patricia, Skodol Andrew E, Kasen Stephanie, Brook Judith S
New York State Psychiatric Institute, Box 60, 1051 Riverside Drive, New York, NY 10032, USA.
Am J Psychiatry. 2005 Oct;162(10):1926-32. doi: 10.1176/appi.ajp.162.10.1926.
The authors investigated 1) whether adolescents and adults in the community diagnosed with personality disorder not otherwise specified are at elevated risk for adverse outcomes, and 2) whether this elevation in risk is comparable with that associated with the DSM-IV cluster A, B, and C personality disorders.
A community-based sample of 693 mothers and their offspring were interviewed during the offspring's childhood, adolescence, and early adulthood. Offspring psychopathology, aggressive behavior, educational and interpersonal difficulties, and suicidal behavior were assessed.
Individuals who met DSM-IV criteria for personality disorder not otherwise specified were significantly more likely than those without personality disorders to have concurrent axis I disorders and behavioral, educational, or interpersonal problems during adolescence and early adulthood. In addition, adolescents with personality disorder not otherwise specified were at significantly elevated risk for subsequent educational failure, numerous interpersonal difficulties, psychiatric disorders, and serious acts of physical aggression by early adulthood. Adolescents with personality disorder not otherwise specified were as likely to have these adverse outcomes as those with cluster A, B, or C personality disorders or those with axis I disorders.
Adolescents and young adults in the general population diagnosed with personality disorder not otherwise specified may be as likely as those with DSM-IV cluster A, B, or C personality disorders to have axis I psychopathology and to have behavioral, educational, or interpersonal problems that are not attributable to co-occurring psychiatric disorders. Individuals with personality disorder not otherwise specified and individuals with DSM-IV cluster A, B, or C personality disorders are likely to be at substantially elevated risk for a wide range of adverse outcomes.
作者调查了1)社区中被诊断为未特定型人格障碍的青少年和成年人是否有更高的不良后果风险,以及2)这种风险升高是否与《精神疾病诊断与统计手册》第四版(DSM-IV)中A、B和C类人格障碍相关的风险相当。
对693名母亲及其子女进行了基于社区的抽样访谈,访谈时间涵盖子女的童年、青少年和成年早期。评估了子女的精神病理学、攻击行为、教育和人际困难以及自杀行为。
符合DSM-IV未特定型人格障碍标准的个体比没有人格障碍的个体在青少年期和成年早期更有可能同时患有轴I障碍以及行为、教育或人际问题。此外,患有未特定型人格障碍的青少年在成年早期出现后续教育失败、众多人际困难、精神障碍以及严重身体攻击行为的风险显著升高。患有未特定型人格障碍的青少年出现这些不良后果的可能性与患有A、B或C类人格障碍的青少年或患有轴I障碍的青少年相当。
普通人群中被诊断为未特定型人格障碍的青少年和年轻人出现轴I精神病理学以及出现并非由同时发生的精神障碍所致的行为、教育或人际问题的可能性,可能与患有DSM-IV中A、B或C类人格障碍的个体相当。患有未特定型人格障碍的个体以及患有DSM-IV中A、B或C类人格障碍的个体很可能面临广泛不良后果的显著更高风险。