Fitzgerald G K
Department of Physical Therapy, School of Health and Rehabilitation Sciences, University of Pittsburgh, PA 15260, USA.
Eura Medicophys. 2005 Jun;41(2):163-71.
While exercise has been shown to be beneficial for reducing pain and improving physical function in individuals with knee osteoarthritis (OA), there are still individuals who do not always respond well to this treatment approach. There are a number of factors that have been shown to influence either the degree of disability and/or the progression of disease in individuals with knee OA. These factors include quadriceps inhibition or activation failure, obesity, passive knee laxity, knee alignment, fear of physical activity and self efficacy. It may be possible that varying levels of these factors might also interfere with an individual's ability to participate in an exercise or physical activity program or minimize the benefits that can be achieved by such programs. This paper examines the influence of these factors on physical function and their potential for altering the outcome of exercise therapy programs for individuals with knee OA. Implications and suggestions for potential adjunctive interventions to address these factors in future research and clinical practice are also discussed.
虽然运动已被证明对减轻膝骨关节炎（OA）患者的疼痛和改善身体功能有益，但仍有一些患者对这种治疗方法反应不佳。有许多因素已被证明会影响膝OA患者的残疾程度和/或疾病进展。这些因素包括股四头肌抑制或激活失败、肥胖、膝关节被动松弛、膝关节对线、对体育活动的恐惧和自我效能感。这些因素的不同水平也可能会干扰个体参与运动或体育活动计划的能力，或使此类计划所能带来的益处降至最低。本文探讨了这些因素对身体功能的影响，以及它们改变膝OA患者运动治疗计划结果的可能性。还讨论了在未来研究和临床实践中针对这些因素进行潜在辅助干预的意义和建议。
