Stokes M Barry
Department of Pathology, Renal Pathology Laboratory, VC14-224, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.
ScientificWorldJournal. 2005 Sep 29;5:828-33. doi: 10.1100/tsw.2005.106.
Proteinuria is common in diabetic patients and usually reflects the presence of diabetic glomerulosclerosis. This paper reviews the differential diagnosis of proteinuria in diabetic patients and discusses the role of renal biopsy examination in identification and management of minimal change disease in this cohort. Identification of nondiabetic glomerular disease requires careful correlation of clinical history and renal biopsy findings and may have important implications for prognosis and therapy.
蛋白尿在糖尿病患者中很常见,通常反映了糖尿病肾小球硬化的存在。本文综述了糖尿病患者蛋白尿的鉴别诊断,并讨论了肾活检检查在该队列微小病变病的识别和管理中的作用。非糖尿病性肾小球疾病的识别需要仔细关联临床病史和肾活检结果,这可能对预后和治疗具有重要意义。