爱泼斯坦-巴尔病毒相关的眼阵挛-肌阵挛-共济失调并不排除隐匿性神经母细胞瘤的存在。

Epstein-Barr virus related opsoclonus-myoclonus-ataxia does not rule out the presence of occult neuroblastic tumors.

作者信息

Cardesa-Salzmann Teresa M, Mora Jaume, García Cazorla M Angels, Cruz Ofelia, Muñoz Carmen, Campistol Jaume

机构信息

Department of Pediatrics, Unitat Integrada Hospital Sant Joan de Déu-Hospital Clínic. University of Barcelona, Barcelona, Spain.

出版信息

Pediatr Blood Cancer. 2006 Dec;47(7):964-7. doi: 10.1002/pbc.20573.

DOI:10.1002/pbc.20573

PMID:16200567

Abstract

Opsoclonus-myoclonus-ataxia (OMA) secondary to Epstein-Barr virus (EBV) infection has only been described in three pediatric patients. Previous reports suggested that evidence for a recent EBV infection in the absence of an occult neoplasm would predict a favorable prognosis for OMA as well as no tumor development. We present the case of a 20-month-old child with OMA associated with a microbiologically documented acute EBV infection and an occult thoracic ganglioneuroblastoma diagnosed 5 months later.

摘要

继发于爱泼斯坦-巴尔病毒（EBV）感染的眼阵挛-肌阵挛-共济失调（OMA）仅在三名儿科患者中被描述过。先前的报告表明，在没有隐匿性肿瘤的情况下，近期EBV感染的证据预示着OMA预后良好且不会发生肿瘤。我们报告了一例20个月大的患有OMA的儿童病例，该病例伴有微生物学记录的急性EBV感染，并在5个月后诊断出隐匿性胸神经节神经母细胞瘤。