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[葡萄膜炎治疗中的问题评估]

[Evaluation of the problems in the treatment of uveitis].

作者信息

Yang Pei-zeng, Wang Hong, Zhou Hong-yan, Yu Qiong, Zhong Hui, Huang Xiang-kun, Fu Tao, Chen Ling

机构信息

Zhongshan Ophthalmic Center, Sun Yat-sen University of Medical Sciences, Guangzhou 510060, China.

出版信息

Zhonghua Yan Ke Za Zhi. 2004 Oct;40(10):679-82.

Abstract

OBJECTIVE

To address the problems present in the treatment of uveitis.

METHODS

A retrospective analysis was made on 154 patients (268 eyes) with different entities of uveitis, coming from all over China and referring to Zhongshan ophthalmic center from April to October of 2000. The data of these patients, especially with respect to the usage of corticosteroids and antibiotics in the referred hospitals, were analyzed.

RESULTS

Corticosteroids drops, subconjunctival or retrobulbar injection and systemic corticosteroids were respectively used in 90.3% and 84.0% of these eyes, and 92.9% of these cases. Intravenous injection of corticosteroids was rather popular, accounting for 85.3% of the cases who were treated with systemic corticosteroids. Improperly aggressive treatment with corticosteroids or undue application of their eye drops was equally found in patients from county-, city- and province-level hospitals, especially in Behcet's disease, anterior uveitis and Fuchs heterochromic uveitis. Antibiotics drops, subconjunctival injection and systemic administration of antibiotics were respectively used in 97.0% and 71.6% of these eyes and 83.8% of these patients. Immunosuppressive drugs, other than the corticosteroids, were used in 6 patients only.

CONCLUSIONS

Corticosteroids should be used in proper methods, dosage and duration based on the entities and severity of uveitis. It is not necessary to treat noninfectious uveitis with antibiotics.

摘要

目的

解决葡萄膜炎治疗中存在的问题。

方法

对2000年4月至10月来自中国各地并转诊至中山眼科中心的154例(268只眼)不同类型葡萄膜炎患者进行回顾性分析。分析这些患者的数据,尤其是在转诊医院中糖皮质激素和抗生素的使用情况。

结果

这些眼中分别有90.3%和84.0%使用了糖皮质激素滴眼液、结膜下或球后注射以及全身用糖皮质激素,这些病例中有92.9%使用了。静脉注射糖皮质激素相当普遍,在接受全身用糖皮质激素治疗的病例中占85.3%。在县级、市级和省级医院的患者中均发现了糖皮质激素使用不当或滴眼液使用过度的情况,尤其是在白塞病、前葡萄膜炎和富克斯异色性葡萄膜炎患者中。这些眼中分别有97.0%和71.6%使用了抗生素滴眼液、结膜下注射和全身使用抗生素,这些患者中有83.8%使用了。除糖皮质激素外,仅6例患者使用了免疫抑制剂。

结论

应根据葡萄膜炎的类型和严重程度,以适当的方法、剂量和疗程使用糖皮质激素。用抗生素治疗非感染性葡萄膜炎没有必要。

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