Kuzela Ladislav, Oltman Marian, Sutka Jarolim, Hrcka Rudolf, Novotna Tatiana, Vavrecka Anton
Clinic of Gastroenterology of the Slovak Health University St. Cyril and Method's Faculty Hospital, Bratislava, Slovak Republic.
Hepatogastroenterology. 2005 Sep-Oct;52(65):1357-61.
BACKGROUND/AIMS: The frequency of iatrogenic postoperative benign strictures has substantially increased in recent years and this is thought to be because of the widespread use of laparoscopic cholecystectomy. Our study was performed prospectively with the goal to investigate the short-term and long-term outcome for endoscopic treatment with insertion of multiple stents in patients with postoperative benign common bile duct stricture after laparoscopic cholecystectomy.
Overall 43 consecutive patients with history of laparoscopic cholecystectomy were enrolled and followed prospectively between December 1998 and December 2003. In all patients a maximum possible number of stents, in relation to the tightness of the stricture and diameter of the bile duct for a period of one year was inserted endoscopically. Patients entered in the follow-up phase after first ERCP procedure with insertion of a biliary plastic stent and continued to be followed after extraction of all stents.
Successful endoscopic dilatation of benign biliary stricture after laparoscopic cholecystectomy with placement of multiple biliary plastic stents was achieved in all 43 patients (100%), with a mean follow-up of 16.0+/-11.1 months (range 1 to 42 months) after stent removal. The mean number of multiple plastic stents inserted in one patients with the goal to achieve maximum stricture dilation was 3.4+/-0.6 (range 3 to 5). No recurrence of biliary stricture during or at the end of follow-up was noticed in any patients (100% success rate).
Endoscopic insertion of maximum number of stents in relation to the tightness of the stricture and diameter of the bile duct is highly effective and may improve long-term results for patients with biliary strictures secondary to laparoscopic cholecystectomy.
背景/目的:近年来,医源性术后良性狭窄的发生率显著增加,这被认为是由于腹腔镜胆囊切除术的广泛应用。我们进行了一项前瞻性研究,旨在调查腹腔镜胆囊切除术后良性胆总管狭窄患者内镜下置入多个支架治疗的短期和长期效果。
1998年12月至2003年12月,共纳入43例有腹腔镜胆囊切除术史的连续患者,并对其进行前瞻性随访。在所有患者中,根据狭窄的严重程度和胆管直径,在内镜下尽可能多地置入支架,持续一年。患者在首次内镜逆行胰胆管造影(ERCP)置入胆管塑料支架后进入随访阶段,在所有支架取出后继续随访。
43例患者(100%)均成功通过内镜扩张腹腔镜胆囊切除术后的良性胆管狭窄,并置入多个胆管塑料支架,支架取出后平均随访16.0±11.1个月(范围1至42个月)。为实现最大程度的狭窄扩张,每位患者置入的多个塑料支架平均数量为3.4±0.6(范围3至5)。所有患者在随访期间或随访结束时均未发现胆管狭窄复发(成功率100%)。
根据狭窄的严重程度和胆管直径在内镜下置入最大数量的支架非常有效,可能改善腹腔镜胆囊切除术后胆管狭窄患者的长期治疗效果。