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经皮治疗良性胆管狭窄。

Percutaneous treatment of benign bile duct strictures.

作者信息

Köcher Martin, Cerná Marie, Havlík Roman, Král Vladimír, Gryga Adolf, Duda Miloslav

机构信息

Department of Radiology, University Hospital, I.P.Pavlova 6, 775 20 Olomouc, Czech Republic.

出版信息

Eur J Radiol. 2007 May;62(2):170-4. doi: 10.1016/j.ejrad.2007.01.032. Epub 2007 Mar 26.

Abstract

PURPOSE

To evaluate long-term results of treatment of benign bile duct strictures.

MATERIALS AND METHODS

From February 1994 to November 2005, 21 patients (9 men, 12 women) with median age of 50.6 years (range 27-77 years) were indicated to percutaneous treatment of benign bile duct stricture. Stricture of hepatic ducts junction resulting from thermic injury during laparoscopic cholecystectomy was indication for treatment in one patient, stricture of hepaticojejunostomy was indication for treatment in all other patients. Clinical symptoms (obstructive jaundice, anicteric cholestasis, cholangitis or biliary cirrhosis) have appeared from 3 months to 12 years after surgery.

RESULTS

Initial internal/external biliary drainage was successful in 20 patients out of 21. These 20 patients after successful initial drainage were treated by balloon dilatation and long-term internal/external drainage. Sixteen patients were symptoms free during the follow-up. The relapse of clinical symptoms has appeared in four patients 9, 12, 14 and 24 months after treatment. One year primary clinical success rate of treatment for benign bile duct stricture was 94%. Additional two patients are symptoms free after redilatation (15 and 45 months). One patient is still in treatment, one patient died during secondary treatment period without interrelation with biliary intervention. The secondary clinical success rate is 100%.

CONCLUSION

Benign bile duct strictures of hepatic ducts junction or biliary-enteric anastomosis are difficult to treat surgically and endoscopically inaccessible. Percutaneous treatment by balloon dilatation and long-term internal/external drainage is feasible in the majority of these patients. It is minimally invasive, safe and effective.

摘要

目的

评估良性胆管狭窄的长期治疗效果。

材料与方法

1994年2月至2005年11月,21例患者(9例男性,12例女性)接受经皮治疗良性胆管狭窄,中位年龄50.6岁(范围27 - 77岁)。1例患者因腹腔镜胆囊切除术期间热损伤导致肝管汇合处狭窄为治疗指征,其他所有患者以肝管空肠吻合术狭窄为治疗指征。临床症状(梗阻性黄疸、无黄疸性胆汁淤积、胆管炎或胆汁性肝硬化)在手术后3个月至12年出现。

结果

21例患者中20例初始内外胆管引流成功。这20例初始引流成功的患者接受了球囊扩张和长期内外引流治疗。16例患者在随访期间无症状。4例患者在治疗后9、12、14和24个月出现临床症状复发。良性胆管狭窄治疗的1年主要临床成功率为94%。另外2例患者在再次扩张后(15和45个月)无症状。1例患者仍在治疗中,1例患者在二次治疗期间死亡,与胆道干预无关联。二次临床成功率为100%。

结论

肝管汇合处或胆肠吻合口的良性胆管狭窄手术治疗困难且内镜难以到达。对大多数此类患者而言,经皮球囊扩张和长期内外引流治疗是可行的。它微创、安全且有效。

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