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[贲门腺癌术后吻合口复发的再手术治疗]

[Re-surgical treatment for postoperative anastomotic recurrence of adenocarcinoma of gastric cardia].

作者信息

Wang Y, Wang L

机构信息

Department of Thoracic Surgery, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100021, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2001 Oct;39(10):775-7.

Abstract

OBJECTIVE

To evaluate indications and approaches of re-surgical treatment for postoperative anastomotic recurrence of adenocarcinoma of the gastric cardia.

METHOD

Clinical date on 23 patients who had received re-surgical treatment for postoperative anastomotic recurrence of adenocarcinoma of the gastric cardia were analyzed retrospectively.

RESULTS

The rate of tumor resection, incidence of complications, and mortality in the patients were 69.6%, 17.4% and 8.7% respectively. The percentage of patients with pleural and peritoneal adhesion was 87.0%. The mean survival time of the patients with tumors resected was 15.0 months, much longer than 4.1 months of the patients who underwent exploration (P < 0.05). The mean survival time of the patients with no lymph node metastasis and those with lymph node metastasis was 21.3 months and 10.2 months respectively (P > 0.05). The mean survival time of the patients with radical resection was 15.8 months, and that of the patients with palliative resection was 13.3 months (P > 0.05).

CONCLUSIONS

Because of extensive pleural and peritoneal adhesion as well as re-building of the alimentary tract, the operation for anastomotic recurrence of adenocarcinoma of the gastric cardia is difficult and the mortality is high. Moreover, the prognosis of the patients with adenocarcinoma of the gastric cardia is poor. Indications for re-surgical treatment should be strictly selected. Operative approach should depend on the stage of disease.

摘要

目的

评估贲门腺癌术后吻合口复发再手术治疗的适应证及手术方式。

方法

回顾性分析23例贲门腺癌术后吻合口复发接受再手术治疗患者的临床资料。

结果

患者的肿瘤切除率、并发症发生率及死亡率分别为69.6%、17.4%和8.7%。胸膜和腹膜粘连患者的比例为87.0%。肿瘤切除患者的平均生存时间为15.0个月,远长于仅行探查患者的4.1个月(P<0.05)。无淋巴结转移患者和有淋巴结转移患者的平均生存时间分别为21.3个月和10.2个月(P>0.05)。根治性切除患者的平均生存时间为15.8个月,姑息性切除患者的平均生存时间为13.3个月(P>0.05)。

结论

由于胸膜和腹膜广泛粘连以及消化道重建,贲门腺癌吻合口复发手术难度大、死亡率高。而且,贲门腺癌患者预后较差。应严格选择再手术治疗的适应证。手术方式应根据疾病分期而定。

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