Zhang D W
Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Zhong Liu Za Zhi. 1988 Sep;10(5):376-8.
A total of 937 patients with adenocarcinoma of the gastric cardia were operated on within a period of 27 years. The overall resectability rate was 74.5%, the operative mobility was 16.0% and the resection mortality was 1.7% (within 30 days postoperatively). The incidences of anastomotic leakage and pulmonary complications were 3.7% and 3.2%, respectively. These two major complications carried mortality rates of 19.2% and 4.8% and accounted for 50% of the post-operative death. The 1-, 3-, 5-, and 10- year survival rates were 66.9%, 30.0%, 19.5% and 10.3%, respectively. The authors advise regular subtotal proximal gastrectomy when the cancer is confined to the stomach only or extends distally within one third of the lesser curvature. The main factors influencing the long-term results are lymph node metastasis, carcinomatous invasion to gastric serosa and the type of resection, either palliative or curative.
在27年的时间里，共有937例贲门腺癌患者接受了手术治疗。总体可切除率为74.5%，手术活动率为16.0%，切除死亡率为1.7%（术后30天内）。吻合口漏和肺部并发症的发生率分别为3.7%和3.2%。这两种主要并发症的死亡率分别为19.2%和4.8%，占术后死亡人数的50%。1年、3年、5年和10年生存率分别为66.9%、30.0%、19.5%和10.3%。作者建议，当癌症仅局限于胃部或向远端延伸至胃小弯的三分之一以内时，应定期进行近端胃次全切除术。影响长期结果的主要因素是淋巴结转移、癌组织侵犯胃浆膜以及切除类型，即姑息性切除或根治性切除。
