Gralewicz Sławomir, Dyzma Michał
Department of Toxicology and Carcinogenesis, Nofer Institute of Occupational Medicine, Lódź, Poland.
Int J Occup Med Environ Health. 2005;18(2):103-13.
Organic solvents pose a considerable health risk for humans. It is due to their ability to cross biological barriers and indisputable toxicity on the one hand, and the wealth of applications and large production and consumption volumes on the other. The primary target of the toxic action of organic solvents is the nervous system. In this paper, some literature data showing that dopaminergic neurons and their projections are particularly susceptible to the toxic solvent action are presented.
有机溶剂对人类健康构成相当大的风险。一方面是因为它们能够穿过生物屏障且具有无可争议的毒性，另一方面是由于其应用广泛以及产量和消费量巨大。有机溶剂毒性作用的主要靶器官是神经系统。本文展示了一些文献数据，表明多巴胺能神经元及其投射对有毒溶剂的作用特别敏感。
