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模拟肌阵挛或病理性惊跳综合征的自发性刺激敏感性抽搐和跳跃。

Voluntary stimulus-sensitive jerks and jumps mimicking myoclonus or pathological startle syndromes.

作者信息

Thompson P D, Colebatch J G, Brown P, Rothwell J C, Day B L, Obeso J A, Marsden C D

机构信息

MRC Human Movement and Balance Unit, National Hospital for Neurology and Neurosurgery, Queen Square, London, U.K.

出版信息

Mov Disord. 1992;7(3):257-62. doi: 10.1002/mds.870070312.

Abstract

Five patients who presented with stimulus-induced jerking as part of an apparent myoclonic or pathological startle syndrome are reported. Neurophysiological observations in these patients suggested the jerks were voluntary in origin. These included (a) variable latencies to the onset of stimulus induced jerks, (b) latencies were greater than that seen in reflex myoclonus of cortical or brainstem origin, and were (c) longer than the fastest voluntary reaction times of normal subjects, (d) variable patterns of muscle recruitment within each jerk and, (e) significant habituation with repeated stimulation. It is argued that these features are consistent with a voluntary origin for the jerks and enable them to be distinguished from the stereotyped electrophysiological characteristics of myoclonus of cortical and brainstem origin. Electrophysiological recordings may help identify patients with this form of psychogenic movement disorder.

摘要

本文报告了5例患者,他们表现为刺激诱发的抽搐,这是明显的肌阵挛或病理性惊跳综合征的一部分。对这些患者的神经生理学观察表明,抽搐起源于自主运动。这些表现包括:(a)刺激诱发抽搐发作的潜伏期可变;(b)潜伏期长于皮质或脑干起源的反射性肌阵挛,且(c)长于正常受试者最快的自主反应时间;(d)每次抽搐中肌肉募集模式可变;以及(e)重复刺激后有明显的习惯化现象。有人认为,这些特征与抽搐的自主起源一致,使其能够与皮质和脑干起源的肌阵挛的刻板电生理特征区分开来。电生理记录可能有助于识别患有这种形式的心因性运动障碍的患者。

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