Lin Xiao-Xia, Zhu Shou-Min
Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou 310016, China.
Zhongguo Zhong Yao Za Zhi. 2005 Aug;30(15):1147-50.
Anthocyanidin is a type of the plant pigments distributed very extensively, in traditional Chinese herbal products as well. In this review was introduced the recently progress in the anti-cancer trials of anthocyanidins, including the anti-oxidation, the prevention of DNA strand scission, stimulation of cell differentiation, induction of cell apoptosis, interference of regulation of cell proliferation, anti-angiogenic property etc, and the research of anti-cancer mechanisms of anthocyanidin and its structure-activity relationship, pointed the foreground of research and development of anti-cancer medicine.
花青素是一类分布非常广泛的植物色素，在传统中草药产品中也有。本文综述了花青素抗癌试验的最新进展，包括抗氧化、预防DNA链断裂、刺激细胞分化、诱导细胞凋亡、干扰细胞增殖调节、抗血管生成特性等，以及花青素抗癌机制及其构效关系的研究，指出了抗癌药物的研发前景。
