Kasiakou Sofia K, Fragoulis Kostas, Tzagarakis George, Mistidis Panagiotis, Kapaskelis Anastasios, Falagas Matthew E
Alfa Institute of Biomedical Sciences (AIBS), Athens, Greece.
Microb Drug Resist. 2005 Fall;11(3):287-9. doi: 10.1089/mdr.2005.11.287.
We report our experience with two cases of fixation device-related orthopedic infections due to multidrug-resistant Acinetobacter baumannii strains. Both patients were successfully treated with intravenous administration of colistin, despite the reported poor penetration of this medication to these tissues, in the old literature. No serious colistin-associated toxicity developed and no recurrence of the infection occurred on follow up.
我们报告了两例因多重耐药鲍曼不动杆菌菌株引起的与固定装置相关的骨科感染的经验。尽管旧文献报道这种药物在这些组织中的渗透性较差，但两名患者均通过静脉注射黏菌素成功治愈。未出现与黏菌素相关的严重毒性反应，随访期间感染也未复发。
