Raat N J H, Berends F, Verhoeven A J, de Korte D, Ince C
Department of Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Transfus Med. 2005 Oct;15(5):419-23. doi: 10.1111/j.1365-3148.2005.00606.x.
In the past decade, studies suggesting a reduced oxygen delivery by stored red blood cell concentrates (RBCCs) have initiated a discussion about the use of fresh versus old blood. We determined whether old RBCCs represent a significant part of the total of RBCCs issued. The age of RBCCs at the time of transfusion was determined in 74 084 units during a 5-year period in the Academic Medical Center, a main Dutch University Hospital. The mean (+/-SD) storage time of the total number of transfused RBCC was 19.4 +/- 7.0 days, and 37% were older than 3 weeks. As more than one-third of the transfused RBCC units are stored for longer than 3 weeks, the research examining differences in oxygen delivery between fresh and stored RBCC is relevant for packed RBC transfusion practice.
在过去十年中，有研究表明储存的红细胞浓缩液（RBCCs）的氧输送能力下降，这引发了关于使用新鲜血液与陈旧血液的讨论。我们确定了陈旧RBCCs是否占所发放RBCCs总量的很大一部分。在荷兰一所主要大学医院学术医疗中心的5年时间里，对74084单位的RBCCs在输血时的年龄进行了测定。所输注的RBCCs总数的平均（±标准差）储存时间为19.4±7.0天，37%的RBCCs储存时间超过3周。由于超过三分之一的输注RBCCs单位储存时间超过3周，因此研究新鲜RBCCs和储存RBCCs之间氧输送差异的研究对于浓缩红细胞输血实践具有重要意义。
