Agnoletti Gabriella, Iserin Laurence, Lafont Antoine, Sidi Daniel, Desnos Michel
Cardiologie Pédiatrique, Necker-Enfants-Malades, et Cardiologie I, Hôpital Européen Georges Pompidou, Paris, France.
J Interv Cardiol. 2005 Oct;18(5):393-5. doi: 10.1111/j.1540-8183.2005.00072.x.
Obstructive sleep apnoea (OSA) is a common sleep disorder often associated with cardiovascular problems. The role of right to left shunt through a patent foramen ovale (PFO) in OSA is still debated. We report the case of a 42-year-old man with OSA, treated by nocturnal continuous airway pressure, who had a PFO and severe dispnoea and desaturation at exercise. Percutaneous closure of PFO leads to immediate and complete resolution of symptoms. Our report shows for the first time that patients with OSA, PFO, and desaturation at exercise should be considered candidates to PFO closure, even in the absence of cerebral events.
阻塞性睡眠呼吸暂停（OSA）是一种常见的睡眠障碍，常与心血管问题相关。卵圆孔未闭（PFO）导致的右向左分流在OSA中的作用仍存在争议。我们报告了一例42岁患有OSA的男性病例，该患者接受夜间持续气道正压通气治疗，存在PFO，且运动时出现严重呼吸困难和血氧饱和度下降。经皮封堵PFO可使症状立即完全缓解。我们的报告首次表明，即使没有脑部事件，患有OSA、PFO且运动时血氧饱和度下降的患者也应被视为PFO封堵的候选者。
