van Schaik Willem, Zwietering Marcel H, de Vos Willem M, Abee Tjakko
Laboratory of Food Microbiology, Wageningen University, Bomenweg 2, 6703 HD Wageningen, The Netherlands.
Appl Environ Microbiol. 2005 Oct;71(10):6427-30. doi: 10.1128/AEM.71.10.6427-6430.2005.
The sigB gene of Bacillus cereus ATCC 14579 encodes the alternative sigma factor sigma(B). Deletion of sigB in B. cereus leads to hyperresistance to hydrogen peroxide. The expression of katA, which encodes one of the catalases of B. cereus, is upregulated in the sigB deletion mutant, and this may contribute to the hydrogen peroxide-resistant phenotype.
蜡样芽孢杆菌ATCC 14579的sigB基因编码替代sigma因子sigma(B)。蜡样芽孢杆菌中sigB的缺失导致对过氧化氢的超抗性。编码蜡样芽孢杆菌一种过氧化氢酶的katA的表达在sigB缺失突变体中上调,这可能导致了过氧化氢抗性表型。