Childs Alex J, Burke James J, Perry Michelle Y, Check William E, Gallup Donald G
Mercer University School of Medicine and Memorial Health University Medical Center, Department of Obstetrics and Gynecology, Savannah, GA 31404, USA.
J Low Genit Tract Dis. 2005 Oct;9(4):236-8. doi: 10.1097/01.lgt.0000179865.98068.32.
We present a case of recurrent colon cancer detected by routine, annual Papanicolaou screening.
A 59-year-old African American woman who had been treated for T2N0M0 (stage II, Dukes A) colon cancer 2 years before to presentation had a Pap smear showing a high-grade squamous intraepithelial lesion with a normal cervical biopsy result. Because of this discrepancy, a loop electrosurgical excision procedure and endocervical curettage were performed and showed atypical glandular cells suspicious for adenocarcinoma. Subsequent colonoscopy showed recurrent adenocarcinoma of the colon. The patient underwent an en-block total abdominal hysterectomy and anterior-perineal resection showing invasion of recurrent colon cancer into the uterus and cervix.
In patients with a history of extrauterine adenocarcinoma, abnormal Pap screening may indicate recurrent or metastatic carcinoma.
我们报告一例通过常规年度巴氏涂片筛查发现的复发性结肠癌病例。
一名59岁的非裔美国女性，在就诊前2年曾接受T2N0M0（II期，杜克A期）结肠癌治疗，巴氏涂片显示高级别鳞状上皮内病变，宫颈活检结果正常。由于这种差异，进行了环形电外科切除术和宫颈管刮除术，结果显示非典型腺细胞，怀疑为腺癌。随后的结肠镜检查显示为结肠癌复发。患者接受了整块全腹子宫切除术和前会阴切除术，结果显示复发性结肠癌侵犯了子宫和宫颈。
有子宫外腺癌病史的患者，巴氏筛查异常可能提示复发或转移性癌。
