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妇女健康倡议(WHI)研究后的激素疗法:巴西妇科医生的看法

Hormone therapy following the Women's Health Initiative (WHI) study: perception of gynecologists in Brazil.

作者信息

Machado R Bonassi, Fernandes C E, Maia E, Melo N R de, Baracat E Chada

机构信息

Department of Gynecology and Obstetrics, Faculty of Medicine, Jundiaí, São Paulo, Brazil.

出版信息

Minerva Ginecol. 2005 Oct;57(5):563-8.

PMID:16205602
Abstract

AIM

The objective of the present study was to evaluate the effects of the Women's Health Initiative (WHI) study on gynecologists in Brazil, with particular emphasis on knowledge, interpretation of the study and attitude regarding hormone therapy (HT).

METHODS

A total of 806 gynecologists were evaluated through questionnaires. For the evaluation, questions regarding his/her degree of knowledge and interpretation of the WHI study, number of prescriptions written for HT and opinion regarding the ideal form of HT following the WHI study were analyzed.

RESULTS

Physicians were found to have a good knowledge of the study (97.6%). The most common interpretation of the results of the WHI study referred to the single HT regimen used in the trial in patients with specific characteristics, this being the response of 66.3% of physicians. There was a reduction of 21.7% in the intention to prescribe HT, with 32.5% of gynecologists reporting changing to a different therapeutic regimen. After the WHI study, the gynecologists showed a preference for low doses of estrogens and progestogens.

CONCLUSIONS

The WHI study had a relevant impact on the attitude of doctors in Brazil.

摘要

目的

本研究的目的是评估妇女健康倡议(WHI)研究对巴西妇科医生的影响,特别关注其对激素疗法(HT)的知识、研究解读及态度。

方法

通过问卷调查对总共806名妇科医生进行评估。在评估中,分析了关于其对WHI研究的知识程度和解读、HT处方数量以及在WHI研究之后对理想HT形式的看法等问题。

结果

发现医生们对该研究有较好的了解(97.6%)。对WHI研究结果最常见的解读是指在具有特定特征的患者中试验所使用的单一HT方案,66.3%的医生持此观点。开具HT的意愿降低了21.7%,32.5%的妇科医生报告已改用不同的治疗方案。在WHI研究之后,妇科医生表现出对低剂量雌激素和孕激素的偏好。

结论

WHI研究对巴西医生的态度产生了相关影响。

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